Endocannabinoids are neuroprotective in vivo and in vitro, but the mechanisms by which
they act are largely unknown. The present study addressed the role of cannabinoid receptors …

The cellular uptake and the intracellular synthesis/degradation of anandamide are crucial
steps for controlling its extracellular level and the duration of its activity. Although the …

Mammalian conception is a complex process regulated by both sexual behavior and reproductive
performance. Alcohol, marijuana and tobacco are among the main factors which affect …

The molecular basis for the control of energy balance by the endocannabinoid anandamide
(AEA) is still unclear. Here, we show that murine 3T3-L1 fibroblasts have the machinery to …

Anandamide (arachidonoylethanolamide, AEA) belongs to an important class of endogenous
lipids including amides and esters of long chain polyunsaturated fatty acids, collectively …

Endocannabinoids represent a class of endogenous lipid mediators, that are involved in
various biological processes, both centrally and peripherally. The prototype member of this …

Anandamide is a lipid messenger that carries out a wide variety of biological functions. It
has been suggested that anandamide accumulation involves binding to a saturable cellular …

We show that a fully functional endocannabinoid system is present in primary human
melanocytes (normal human epidermal melanocyte cells), including anandamide (AEA), 2-…

Type 1 cannabinoid receptors (CB1R) are G‐protein‐coupled receptors that mediate several
actions of the endocannabinoid anandamide (N‐arachidonoylethanolamine; AEA) in the …

Anandamide (AEA) is an endogenous agonist of type 1 cannabinoid receptors (CB1R) that,
along with metabolic enzymes of AEA and congeners, compose the "endocannabinoid …