Cellular growth in human placenta: I. Normal Placental growth
M Winick, A Coscia, A Noble - Pediatrics, 1967 - publications.aap.org
Fifty normal human placentae from various gestations were analyzed for total DNA, RNA,
and protein content. The data indicate that, although weight, RNA, and protein continue to
increase linearly until term, the rate of increase in DNA rapidly declines when the placenta
reaches about 300 gm or the fetus 2,300 gm. When these data are interpreted in terms of
number and size of cells they suggest that cell division stops in human placenta about 1
month prior to term. The latter portion of placental growth is by enlargement of already …
and protein content. The data indicate that, although weight, RNA, and protein continue to
increase linearly until term, the rate of increase in DNA rapidly declines when the placenta
reaches about 300 gm or the fetus 2,300 gm. When these data are interpreted in terms of
number and size of cells they suggest that cell division stops in human placenta about 1
month prior to term. The latter portion of placental growth is by enlargement of already …