Lung surfactant: Function and composition in the context of development and respiratory physiology
W Bernhard - Annals of Anatomy-Anatomischer Anzeiger, 2016 - Elsevier
Lung surfactant is a complex with a unique phospholipid and protein composition. Its
specific function is to reduce surface tension at the pulmonary air–liquid interface. The …
specific function is to reduce surface tension at the pulmonary air–liquid interface. The …
Choline and choline-related nutrients in regular and preterm infant growth
W Bernhard, CF Poets, AR Franz - European journal of nutrition, 2019 - Springer
Background Choline is an essential nutrient, with increased requirements during
development. It forms the headgroup of phosphatidylcholine and sphingomyelin in all …
development. It forms the headgroup of phosphatidylcholine and sphingomyelin in all …
Commercial versus native surfactants: surface activity, molecular components, and the effect of calcium
W Bernhard, J Mottaghian, A Gebert… - American Journal of …, 2000 - atsjournals.org
Despite their broad clinical use, there is no standardized comparative study on the
functional, biochemical, and morphologic differences of the various commercial surfactants …
functional, biochemical, and morphologic differences of the various commercial surfactants …
From birds to humans: new concepts on airways relative to alveolar surfactant
W Bernhard, PL Haslam, J Floros - American journal of respiratory …, 2004 - atsjournals.org
Pulmonary surfactant is a surface-active mixture of phospholipids and specific proteins that
lines the epithelial surfaces of mammalian lungs. In the alveoli, its main function is to reduce …
lines the epithelial surfaces of mammalian lungs. In the alveoli, its main function is to reduce …
[HTML][HTML] Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo [S]
CJ Pynn, NG Henderson, H Clark, G Koster… - Journal of lipid …, 2011 - ASBMB
Phosphatidylcholine (PC) synthesis by the direct cytidine diphosphate choline (CDP-
choline) pathway in rat liver generates predominantly mono-and di-unsaturated molecular …
choline) pathway in rat liver generates predominantly mono-and di-unsaturated molecular …
Oxidative stress markers and micronutrients in maternal and cord blood in relation to neonatal outcome
D Weber, W Stuetz, W Bernhard, A Franz… - European journal of …, 2014 - nature.com
Results: Maternal protein concentration, PrCarb, MDA and all lipid-soluble micronutrients
were significantly higher compared with newborns, except for 3NT, which was significantly …
were significantly higher compared with newborns, except for 3NT, which was significantly …
Phosphatidylcholine molecular species in lung surfactant: composition in relation to respiratory rate and lung development
W Bernhard, S Hoffmann, H Dombrowsky… - American journal of …, 2001 - atsjournals.org
Surfactant reduces surface tension at the air–liquid interface of lung alveoli. While
dipalmitoylphosphatidylcholine (PC16: 0/16: 0) is its main component, proteins and other …
dipalmitoylphosphatidylcholine (PC16: 0/16: 0) is its main component, proteins and other …
Conductive airway surfactant: surface-tension function, biochemical composition, and possible alveolar origin
W Bernhard, HP Haagsman, T Tschernig… - American journal of …, 1997 - atsjournals.org
Alveolar surfactant is well known for its ability to reduce minimal surface tension at the
alveolar air–liquid interface to values below 5 mN/m. In addition, it has been suggested that …
alveolar air–liquid interface to values below 5 mN/m. In addition, it has been suggested that …
Dipalmitoylphosphatidylcholine is not the major surfactant phospholipid species in all mammals
Pulmonary surfactant, a complex mixture of lipids and proteins, lowers the surface tension in
terminal air spaces and is crucial for lung function. Within an animal species, surfactant …
terminal air spaces and is crucial for lung function. Within an animal species, surfactant …
Pulmonary surfactant in birds: coping with surface tension in a tubular lung
W Bernhard, A Gebert, G Vieten… - American Journal …, 2001 - journals.physiology.org
As birds have tubular lungs that do not contain alveoli, avian surfactant predominantly
functions to maintain airflow in tubes rather than to prevent alveolar collapse. Consequently …
functions to maintain airflow in tubes rather than to prevent alveolar collapse. Consequently …