[HTML][HTML] Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis

C Ovadia, J Sajous, PT Seed, K Patel… - The lancet …, 2021 - thelancet.com
Background Ursodeoxycholic acid is commonly used to treat intrahepatic cholestasis of
pregnancy, yet its largest trial detected minimal benefit for a composite outcome (stillbirth …

[HTML][HTML] Metformin versus insulin for the treatment of gestational diabetes

JA Rowan, WM Hague, W Gao… - New England Journal …, 2008 - Mass Medical Soc
Background Metformin is a logical treatment for women with gestational diabetes mellitus,
but randomized trials to assess the efficacy and safety of its use for this condition are lacking …

Calcium Supplementation In Nulliparous Women For The Prevention Of Pregnancy‐Induced Hypertension, Preeclampsia And Preterm Birth: An Australian …

CA Crowther, JE Hiller, B Pridmore… - Australian and New …, 1999 - Wiley Online Library
A multicentre, randomized controlled double‐blind trial in 5 maternity hospitals in Australia
assessed the effect of a daily supplement of calcium (1.8 g oral calcium or an oral placebo) …

Pharmacological interventions for treating intrahepatic cholestasis of pregnancy

KF Walker, LC Chappell, WM Hague… - Cochrane Database …, 2020 - cochranelibrary.com
Background Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder that can develop
in pregnancy. It occurs when there is a build‐up of bile acids in the maternal blood. It has …

Treatment of gestational diabetes mellitus diagnosed early in pregnancy

D Simmons, J Immanuel, WM Hague… - … England Journal of …, 2023 - Mass Medical Soc
Background Whether treatment of gestational diabetes before 20 weeks' gestation improves
maternal and infant health is unclear. Methods We randomly assigned, in a 1: 1 ratio …

[HTML][HTML] Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data …

C Ovadia, PT Seed, A Sklavounos, V Geenes, C Di Ilio… - The Lancet, 2019 - thelancet.com
Background Intrahepatic cholestasis of pregnancy is associated with adverse perinatal
outcomes, but the association with the concentration of specific biochemical markers is …

Metformin in gestational diabetes: the offspring follow-up (MiG TOFU) body composition at 2 years of age

JA Rowan, EC Rush, V Obolonkin, M Battin… - Diabetes …, 2011 - Am Diabetes Assoc
OBJECTIVE In women with gestational diabetes mellitus, who were randomized to
metformin or insulin treatment, pregnancy outcomes were similar (Metformin in Gestational …

Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational …

MA Rodger, WM Hague, SR Kahn, A Karovitch… - The Lancet, 2014 - thelancet.com
Background Thrombophilias are common disorders that increase the risk of pregnancy-
associated venous thromboembolism and pregnancy loss and can also increase the risk of …

Metformin in gestational diabetes: the offspring follow-up (MiG TOFU): body composition and metabolic outcomes at 7–9 years of age

JA Rowan, EC Rush, LD Plank, J Lu… - BMJ Open Diabetes …, 2018 - drc.bmj.com
Objective To compare body composition and metabolic outcomes at 7–9 years in offspring of
women with gestational diabetes (GDM) randomized to metformin (±insulin) or insulin …

The prevalence of polycystic ovaries in patients with congenital adrenal hyperplasia and their close relatives

WM Hague, J Adams, C Rodda, CG Brook… - Clinical …, 1990 - Wiley Online Library
Seventy‐seven female patients (36 adults and 41 children aged under 16 years) with
congenital adrenal hyperplasia (CAH) were assessed using pelvic ultrasound, as well as …