Personalized medicine for the management of RDS in preterm neonates

D De Luca, C Autilio, L Pezza, S Shankar-Aguilera… - Neonatology, 2021 - karger.com
Continuous positive airway pressure and surfactant represent the first-and second-line
treatment for respiratory distress syndrome in preterm neonates, as European and American …

Structural position and amount of palmitic acid in infant formulas: effects on fat, fatty acid, and mineral balance

VP Carnielli, IHT Luijendijk… - Journal of pediatric …, 1996 - journals.lww.com
The structure of the triglycerides (TG) in human milk (HM) differs from those of vegetable oils
used in infant formulas. In HM, palmitic acid is predominantly esterified to the center or β …

The Montreux definition of neonatal ARDS: biological and clinical background behind the description of a new entity

D De Luca, AH Van Kaam, DG Tingay… - The Lancet …, 2017 - thelancet.com
Acute respiratory distress syndrome (ARDS) is undefined in neonates, despite the long-
standing existing formal recognition of ARDS syndrome in later life. We describe the …

Aspiration lung disease

FM de Benedictis, VP Carnielli… - Pediatric Clinics of North …, 2009 - Elsevier
The term aspiration lung disease describes several clinical syndromes, with massive
aspiration and chronic lung aspiration being at two extremes of the clinical spectrum. Over …

Less invasive surfactant administration: a word of caution

D De Luca, S Shankar-Aguilera… - The Lancet Child & …, 2020 - thelancet.com
Surfactant is a cornerstone of neonatal critical care, and the presumed less (or minimally)
invasive techniques for its administration have been proposed to reduce invasiveness of …

[HTML][HTML] The very low birth weight premature infant is capable of synthesizing arachidonic and docosahexaenoic acids from linoleic and linolenic acids

VP Carnielli, DJL Wattimena, IHT Luijendijk… - Pediatric …, 1996 - nature.com
Infants fed formulas devoid of long-chain polyunsaturated fatty acids (LCP) exhibit low
plasma LCP concentrations and have poorer retinal and neurologic development in …

Feeding premature newborn infants palmitic acid in amounts and stereoisomeric position similar to that of human milk: effects on fat and mineral balance

VP Carnielli, IH Luijendijk, JB van Goudoever… - The American journal of …, 1995 - Elsevier
The effect of the structure of human milk triglycerides on intestinal fat absorption remains
controversial. Twelve infants were each fed, for 1 wk in a crossover design, two formulas that …

Lung ultrasound to monitor extremely preterm infants and predict bronchopulmonary dysplasia. A multicenter longitudinal cohort study

B Loi, G Vigo, E Baraldi, F Raimondi… - American journal of …, 2021 - atsjournals.org
Rationale: Lung ultrasound is useful in critically ill patients with acute respiratory failure.
Given its characteristics, it could also be useful in extremely preterm infants with evolving …

European consensus guidelines on the management of respiratory distress syndrome: 2022 update

DG Sweet, VP Carnielli, G Greisen, M Hallman… - Neonatology, 2023 - karger.com
Respiratory distress syndrome (RDS) care pathways evolve slowly as new evidence
emerges. We report the sixth version of “European Guidelines for the Management of RDS” …

[HTML][HTML] Synthesis of long-chain polyunsaturated fatty acids in preterm newborns fed formula with long-chain polyunsaturated fatty acids

VP Carnielli, M Simonato, G Verlato, I Luijendijk… - The American journal of …, 2007 - Elsevier
Background: Docosahexaenoic acid (DHA) and arachidonic acid (AA) are long-chain
polyunsaturated fatty acids (LCPs) that play pivotal roles in growth and neurodevelopment …