Reflexes that impact spontaneous breathing of preterm infants at birth: a narrative review

K Kuypers, T Martherus, T Lamberska… - Archives of Disease in …, 2020 - fn.bmj.com
Some neural circuits within infants are not fully developed at birth, especially in preterm
infants. Therefore, it is unclear whether reflexes that affect breathing may or may not be …

Supporting breathing of preterm infants at birth: a narrative review

T Martherus, A Oberthuer, J Dekker… - Archives of Disease in …, 2019 - fn.bmj.com
Most very preterm infants have difficulty aerating their lungs and require respiratory support
at birth. Currently in clinical practice, non-invasive ventilation in the form of continuous …

[HTML][HTML] The effect of a face mask for respiratory support on breathing in preterm infants at birth

KLAM Kuypers, T Lamberska, T Martherus, J Dekker… - Resuscitation, 2019 - Elsevier
Objective Applying a mask on the face for respiratory support could induce a
trigeminocardiac reflex leading to apnoea and bradycardia. We have examined the effect of …

[HTML][HTML] Repetitive versus standard tactile stimulation of preterm infants at birth–a randomized controlled trial

J Dekker, SB Hooper, T Martherus, SJE Cramer… - Resuscitation, 2018 - Elsevier
Aim To evaluate the direct effect of repetitive tactile stimulation on breathing effort of preterm
infants at birth. Methods This randomized controlled trial compared the effect of repetitive …

[HTML][HTML] The Effect of Initial High vs. Low FiO2 on Breathing Effort in Preterm Infants at Birth: A Randomized Controlled Trial

J Dekker, T Martherus, E Lopriore, M Giera… - Frontiers in …, 2019 - frontiersin.org
Background: Infants are currently stabilized at birth with initial low FiO2 which increases the
risk of hypoxia and suppression of breathing in the first minutes after birth. We hypothesized …

[HTML][HTML] Tactile stimulation to stimulate spontaneous breathing during stabilization of preterm infants at birth: a retrospective analysis

J Dekker, T Martherus, SJE Cramer… - Frontiers in …, 2017 - frontiersin.org
Background and aims Tactile maneuvers to stimulate breathing in preterm infants are
recommended during the initial assessment at birth, but it is not known how often and how …

[HTML][HTML] Increasing respiratory effort with 100% oxygen during resuscitation of preterm rabbits at birth

J Dekker, SB Hooper, MK Croughan… - Frontiers in …, 2019 - frontiersin.org
Background: Spontaneous breathing is essential for successful non-invasive respiratory
support delivered by a facemask at birth. As hypoxia is a potent inhibitor of spontaneous …

[HTML][HTML] Comparison of two respiratory support strategies for stabilization of very preterm infants at birth: a matched-pairs analysis

T Martherus, A Oberthuer, J Dekker… - Frontiers in …, 2019 - frontiersin.org
Objective: Respiratory support for stabilizing very preterm infants at birth varies between
centers. We retrospectively compared two strategies that involved either increasing …

[HTML][HTML] Technology in the delivery room supporting the neonatal healthcare provider's task

SJE Cramer, KLAM Kuypers, T Martherus… - Seminars in Fetal and …, 2022 - Elsevier
Very preterm infants are a unique and highly vulnerable group of patients that have a narrow
physiological margin within which interventions are safe and effective. The increased …

[HTML][HTML] High-CPAP does not impede cardiovascular changes at birth in preterm sheep

T Martherus, KJ Crossley, KA Rodgers, J Dekker… - Frontiers in …, 2021 - frontiersin.org
Objective: Continuous positive airway pressures (CPAP) used to assist preterm infants at
birth are limited to 4–8 cmH2O due to concerns that high-CPAP may cause pulmonary …