Executive summary A concerted effort to tackle the global health problem posed by traumatic
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …

Background There is considerable uncertainty regarding the optimal haemoglobin threshold
for the use of red blood cell (RBC) transfusions in anaemic patients. Blood is a scarce …

Aims To provide systematic assessment of the safety and efficacy of autologous bone
marrow-derived stem cell (BMSC) transplantation in acute myocardial infarction (AMI) based …

Background Fresh red cells may improve outcomes in critically ill patients by enhancing
oxygen delivery while minimizing the risks of toxic effects from cellular changes and the …

Background The effectiveness of platelet transfusions to prevent bleeding in patients with
hematologic cancers remains unclear. This trial assessed whether a policy of not giving …

Objective: To identify an appropriate diagnostic tool for the early diagnosis of acute traumatic
coagulopathy and validate this modality through prediction of transfusion requirements in …

The COVID-19 pandemic has major implications for blood transfusion. There are uncertain
patterns of demand, and transfusion institutions need to plan for reductions in donations and …

Blood transfusion is one of the most common procedures in patients in hospital so it is
imperative that clinicians are knowledgeable about appropriate blood product …

Background Recombinant factor VIIa (rFVIIa) is licensed for use in patients with haemophilia
and inhibitory allo‐antibodies. It is also increasingly being used for off‐license indications to …

1NHS Blood and Transplant, 2Imperial College Healthcare NHS Trust, London, 3University
College Hospitals NHS Trust, London, 4Serious Hazards of Transfusion, NHS Blood and …