Risk factors for pediatric extubation failure: the importance of respiratory muscle strength

RG Khemani, T Sekayan, J Hotz, RC Flink… - Critical care …, 2017 - journals.lww.com
Objective: Respiratory muscle weakness frequently develops during mechanical ventilation,
although in children there are limited data about its prevalence and whether it is associated …

[HTML][HTML] Pediatric extubation readiness tests should not use pressure support

RG Khemani, J Hotz, R Morzov, RC Flink… - Intensive care …, 2016 - Springer
Purpose Pressure support is often used for extubation readiness testing, to overcome
perceived imposed work of breathing from endotracheal tubes. We sought to determine …

Effort and work-of-breathing parameters strongly correlate with increased resistance in an animal model

RC Flink, CJL Newth, JC Hotz, MCJ Kneyber… - Pediatric …, 2023 - nature.com
Abstract Background Effort of Breathing (EOB) calculations may be a reliable alternative to
Work of Breathing (WOB) calculations in which Respiratory Inductance Plethysmography …

A humidifier in the invasive mode during noninvasive respiratory support could increase condensation and thereby impair airway patency

RC Flink, AH van Kaam, FH de Jongh - Acta Paediatrica, 2018 - Wiley Online Library
Aim Humidifying noninvasively ventilated preterm infants is critical to prevent dehydration of
respiratory mucosa, but over‐humidification can result in impaired airway patency and lung …

In vitro study on work of breathing during non-invasive ventilation using a new variable flow generator

RC Flink, AH van Kaam, FH de Jongh - Archives of Disease in …, 2015 - fn.bmj.com
Objective In an attempt to reduce the work of breathing (WOB) and the risk of respiratory
failure, preterm infants are increasingly treated with nasal synchronised biphasic positive …

Comparison Of The Dose Response Changes To Effort And Work-Of-Breathing Parameters In An Animal Model Of Extrathoracic Upper Airway Obstruction

RC Flink, RG Khemani, J Hotz, P Ross… - … AND CRITICAL CARE, 2017 - atsjournals.org
Work of Breathing (WOB) measurements may be helpful in a variety of disease conditions,
but accurate measurement requires esophageal pressure and spirometry. While it may be …

[CITATION][C] Reply from the authors: Additional factors to consider with regard to condensation in bench studies.

RC Flink, AH van Kaam, FH de Jongh - Acta Paediatrica (Oslo …, 2018 - europepmc.org
This is a comment on" Additional factors to consider while providing humidification support
to neonates." Acta Paediatr. 2019 Feb; 108 (2): 379. This is a comment on" A humidifier in …