User profiles for "author:Rolf Groenwold"

Rolf Groenwold

professor of Clinical Epidemiology, LUMC, Leiden University
Verified email at lumc.nl
Cited by 13689

[HTML][HTML] Overestimation of risk ratios by odds ratios in trials and cohort studies: alternatives to logistic regression

MJ Knol, S Le Cessie, A Algra, JP Vandenbroucke… - Cmaj, 2012 - Can Med Assoc
Analysis domly assigned to groups receiving surgery followed by radiotherapy, or
radiotherapy alone. 12 The primary outcome was the ability to walk, which occurred in …

[HTML][HTML] Missing covariate data in clinical research: when and when not to use the missing-indicator method for analysis

RHH Groenwold, IR White, ART Donders… - Cmaj, 2012 - Can Med Assoc
If missingness of a variable is related to observed characteristics but not to unobserved
characteristics, the data are (confusingly) called “missing at random.” 2, 5, 6 If data are …

Get real in individual participant data (IPD) meta‐analysis: a review of the methodology

TPA Debray, KGM Moons… - Research synthesis …, 2015 - Wiley Online Library
Individual participant data (IPD) meta‐analysis is an increasingly used approach for
synthesizing and investigating treatment effect estimates. Over the past few years, numerous …

Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies

WG Melsen, MM Rovers, RHH Groenwold… - The Lancet infectious …, 2013 - thelancet.com
Background Estimating attributable mortality of ventilator-associated pneumonia has been
hampered by confounding factors, small sample sizes, and the difficulty of doing relevant …

[HTML][HTML] Estimating measures of interaction on an additive scale for preventive exposures

MJ Knol, TJ VanderWeele, RHH Groenwold… - European journal of …, 2011 - Springer
Measures of interaction on an additive scale (relative excess risk due to interaction [RERI],
attributable proportion [AP], synergy index [S]), were developed for risk factors rather than …

Dealing with missing outcome data in randomized trials and observational studies

RHH Groenwold, ART Donders… - American journal of …, 2012 - academic.oup.com
Although missing outcome data are an important problem in randomized trials and
observational studies, methods to address this issue can be difficult to apply. Using …

Do self-management interventions work in patients with heart failure? An individual patient data meta-analysis

NH Jonkman, H Westland, RHH Groenwold, S Ågren… - Circulation, 2016 - Am Heart Assoc
Background—Self-management interventions are widely implemented in the care for
patients with heart failure (HF). However, trials show inconsistent results, and whether …

Operative treatment versus nonoperative treatment of Achilles tendon ruptures: systematic review and meta-analysis

Y Ochen, RB Beks, M van Heijl, F Hietbrink… - Bmj, 2019 - bmj.com
Objectives To compare re-rupture rate, complication rate, and functional outcome after
operative versus nonoperative treatment of Achilles tendon ruptures; to compare re-rupture …

Benzodiazepine-associated delirium in critically ill adults

IJ Zaal, JW Devlin, M Hazelbag… - Intensive care …, 2015 - Springer
Purpose The association between benzodiazepine use and delirium risk in the ICU remains
unclear. Prior investigations have failed to account for disease severity prior to delirium …

Reporting of covariate selection and balance assessment in propensity score analysis is suboptimal: a systematic review

MS Ali, RHH Groenwold, SV Belitser… - Journal of clinical …, 2015 - Elsevier
Objectives To assess the current practice of propensity score (PS) analysis in the medical
literature, particularly the assessment and reporting of balance on confounders. Study …