The pharmacokinetic profile of caffeine was studied in 32 premature newborn infants with
apnea: 12 following a single intravenous dose; 3 after a single oral dose; 7 during treatment …

In addition to their intrinsic value as probes in the study of differentiation, the interactions
between xenobiotics and the developing organism are of immediate therapeutic and …

To characterize further the pharmacokinetics of theophylline in premature infants, its
concentration in blood was measured by high-pressure liquid chromatography after …

The pharmacokinetic profile of phenytoin (DPH) was studied in 30 infants aged 2 days to 96
weeks. The plasma DPH half-life during the first week of life in term infants was prolonged …

Therapeutic lung lavage is an emerging treatment for meconium aspiration syndrome. Our
objective was to investigate the type of fluid and aliquot volume most appropriate for lung …

Aim: To explore the effects of a large volume lung lavage procedure in ventilated infants with
meconium aspiration syndrome. Methods: Infants with severe meconium aspiration requiring …

Objective: To examine hemodynamic changes following endovascular embolization in
newborn infants with vein of Galen malformation and severe cardiac failure in the first week …

Rationale High‐frequency jet ventilation (HFJV) is often used to treat infants with
pathologies associated with gas trapping and abnormal lung mechanics, who are sensitive …

Sweet-tasting solutions such as sucrose and glucose have been shown in a large number of
studies to be efficacious in reducing procedurerelated pain in newborn infants. 1 However …

CONCLUSIONS: 1) DNS is a more effective lavage fluid than PSE, both in terms of more
sustained improvement in lung function, and more effective removal of meconium. 2) …