[HTML][HTML] Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis

C Ovadia, J Sajous, PT Seed, K Patel… - The lancet …, 2021 - thelancet.com
Background Ursodeoxycholic acid is commonly used to treat intrahepatic cholestasis of
pregnancy, yet its largest trial detected minimal benefit for a composite outcome (stillbirth …

Antiplatelet agents and the prevention of spontaneous preterm birth: a systematic review and meta-analysis

EOG Van Vliet, LA Askie, BWJ Mol… - Obstetrics & …, 2017 - journals.lww.com
OBJECTIVE: Spontaneous preterm birth is an important cause of neonatal mortality and
morbidity. An increasing body of evidence suggests that uteroplacental ischemia plays an …

Vulnerability of pregnant women in clinical research

ISE Van der Zande, R van der Graaf… - Journal of medical …, 2017 - jme.bmj.com
Background Notwithstanding the need to produce evidence-based knowledge on
medications for pregnant women, they remain underrepresented in clinical research …

[HTML][HTML] Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data …

C Ovadia, PT Seed, A Sklavounos, V Geenes, C Di Ilio… - The Lancet, 2019 - thelancet.com
Background Intrahepatic cholestasis of pregnancy is associated with adverse perinatal
outcomes, but the association with the concentration of specific biochemical markers is …

Intrahepatic cholestasis of pregnancy: maternal and fetal outcomes associated with elevated bile acid levels

L Brouwers, MPH Koster… - American journal of …, 2015 - Elsevier
Objective The primary aim of this study was to investigate the correlation between
pregnancy outcome and bile acid (BA) levels in pregnancies that were affected by …

Foley catheter versus vaginal prostaglandin E2 gel for induction of labour at term (PROBAAT trial): an open-label, randomised controlled trial

M Jozwiak, KO Rengerink, M Benthem, E Van Beek… - The Lancet, 2011 - thelancet.com
Background Induction of labour is a common obstetric procedure. Both mechanical (eg,
Foley catheters) and pharmacological methods (eg, prostaglandins) are used for induction …

Maternal and neonatal consequences of treated and untreated asymptomatic bacteriuria in pregnancy: a prospective cohort study with an embedded randomised …

BM Kazemier, FN Koningstein… - The Lancet Infectious …, 2015 - thelancet.com
Background Existing approaches for the screening and treatment of asymptomatic
bacteriuria in pregnancy are based on trials that were done more than 30 years ago. In this …

Immediate delivery versus expectant monitoring for hypertensive disorders of pregnancy between 34 and 37 weeks of gestation (HYPITAT-II): an open-label …

K Broekhuijsen, GJ van Baaren, MG Van Pampus… - The Lancet, 2015 - thelancet.com
Background There is little evidence to guide the management of women with hypertensive
disorders in late preterm pregnancy. We investigated the effect of immediate delivery versus …

Amiodarone therapy for drug-refractory fetal tachycardia

JF Strasburger, BF Cuneo, MM Michon, NL Gotteiner… - Circulation, 2004 - Am Heart Assoc
Background—Fetal tachycardia complicated by ventricular dysfunction and hydrops fetalis
carries a significant risk of morbidity and mortality. Transplacental digoxin is effective therapy …

Earlier age of onset of chronic hypertension and type 2 diabetes mellitus after a hypertensive disorder of pregnancy or gestational diabetes mellitus

KY Heida, A Franx, BB Van Rijn, MJC Eijkemans… - …, 2015 - Am Heart Assoc
A prospective cohort study was conducted to assess the impact of a history of hypertensive
disorder of pregnancy (HDP) or gestational diabetes mellitus (GDM) on the risk and age of …