Obesity in women of reproductive age is increasing in prevelance worldwide. Obesity
reduces fertility and increases time taken to conceive, and obesity-related comorbidities …

A woman who is healthy at the time of conception is more likely to have a successful
pregnancy and a healthy child. We reviewed published evidence and present new data from …

Objective To provide an accurate assessment of complications of pregnancy in women with
chronic hypertension, including comparison with population pregnancy data (US) to inform …

Background Oxidative stress has been implicated in the pathophysiology of pre-eclampsia.
This randomised controlled trial investigated the effect of supplementation with vitamins C …

Maternal obesity is increasingly prevalent and may affect the long-term health of the child.
We investigated the effects of maternal diet-induced obesity in mice on offspring metabolic …

Background Oxidative stress could play a part in pre-eclampsia, and there is some evidence
to suggest that vitamin C and vitamin E supplements could reduce the risk of the disorder …

Miscarriage and pre-eclampsia are the most common disorders of human pregnancy. Both
are placental-related and exceptional in other mammalian species. Ultrasound imaging has …

Background Behavioural interventions might improve clinical outcomes in pregnant women
who are obese. We aimed to investigate whether a complex intervention addressing diet …

The incidence of the metabolic syndrome, a cluster of abnormalities focusing on insulin
resistance and associated with high risk for cardiovascular disease and diabetes, is …

Objectives To develop a predictive model for pre-eclampsia based on clinical risk factors for
nulliparous women and to identify a subgroup at increased risk, in whom specialist referral …