[PDF][PDF] A functional classification scheme for beta-lactamases and its correlation with molecular structure
K Bush, GA Jacoby, AA Medeiros - Antimicrobial agents and …, 1995 - Am Soc Microbiol
A classification scheme for-lactamases based on functional characteristics is presented.
Three major groups of enzymes are defined by their substrate and inhibitor profiles: group 1 …
Three major groups of enzymes are defined by their substrate and inhibitor profiles: group 1 …
Updated functional classification of β-lactamases
K Bush, GA Jacoby - Antimicrobial agents and chemotherapy, 2010 - Am Soc Microbiol
Two classification schemes for β-lactamases are currently in use. The molecular
classification is based on the amino acid sequence and divides β-lactamases into class A …
classification is based on the amino acid sequence and divides β-lactamases into class A …
Carbapenemases: the versatile β-lactamases
AM Queenan, K Bush - Clinical microbiology reviews, 2007 - Am Soc Microbiol
Carbapenemases are β-lactamases with versatile hydrolytic capacities. They have the ability
to hydrolyze penicillins, cephalosporins, monobactams, and carbapenems. Bacteria …
to hydrolyze penicillins, cephalosporins, monobactams, and carbapenems. Bacteria …
The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking
K Bush, DR Kivlahan, MB McDonell… - Archives of internal …, 1998 - jamanetwork.com
Objective To evaluate the 3 alcohol consumption questions from the Alcohol Use Disorders
Identification Test (AUDIT-C) as a brief screening test for heavy drinking and/or active …
Identification Test (AUDIT-C) as a brief screening test for heavy drinking and/or active …
[HTML][HTML] Peroxynitrite oxidation of sulfhydryls.: The cytotoxic potential of superoxide and nitric oxide
R Radi, JS Beckman, KM Bush, BA Freeman - Journal of Biological …, 1991 - Elsevier
Peroxynitrite anion (ONOO-) is a potent oxidant that mediates oxidation of both nonprotein
and protein sulfhydryls. Endothelial cells, macrophages, and neutrophils can generate …
and protein sulfhydryls. Endothelial cells, macrophages, and neutrophils can generate …
Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide
R Radi, JS Beckman, KM Bush, BA Freeman - Archives of biochemistry and …, 1991 - Elsevier
Endothelial cells, macrophages, neutrophils, and neuronal cells generate superoxide (O 2−)
and nitric oxide (· NO) which can combine to form peroxynitrite anion (ONOO−) …
and nitric oxide (· NO) which can combine to form peroxynitrite anion (ONOO−) …
Novel Carbapenem-Hydrolyzing β-Lactamase, KPC-1, from a Carbapenem-Resistant Strain of Klebsiella pneumoniae
ABSTRACT A Klebsiella pneumoniae isolate showing moderate to high-level imipenem and
meropenem resistance was investigated. The MICs of both drugs were 16 μg/ml. The β …
meropenem resistance was investigated. The MICs of both drugs were 16 μg/ml. The β …
23.6%-efficient monolithic perovskite/silicon tandem solar cells with improved stability
As the record single-junction efficiencies of perovskite solar cells now rival those of copper
indium gallium selenide, cadmium telluride and multicrystalline silicon, they are becoming …
indium gallium selenide, cadmium telluride and multicrystalline silicon, they are becoming …
Tackling antibiotic resistance
The development and spread of antibiotic resistance in bacteria is a universal threat to both
humans and animals that is generally not preventable but can nevertheless be controlled …
humans and animals that is generally not preventable but can nevertheless be controlled …
Perovskite-perovskite tandem photovoltaics with optimized band gaps
We demonstrate four-and two-terminal perovskite-perovskite tandem solar cells with ideally
matched band gaps. We develop an infrared-absorbing 1.2–electron volt band-gap …
matched band gaps. We develop an infrared-absorbing 1.2–electron volt band-gap …