[HTML][HTML] Health related quality of life in people with advanced chronic liver disease

JG Orr, T Homer, L Ternent, J Newton, CJ McNeil… - Journal of …, 2014 - Elsevier
Cirrhosis has a long natural history with considerable symptomatic impacts, particularly in
advancing disease. Measuring health related quality of life (HRQOL) in liver disease …

Orthostatic hypotension and cognitive impairment in Parkinson's disease: causation or association?

C McDonald, JL Newton, DJ Burn - Movement Disorders, 2016 - Wiley Online Library
Orthostatic hypotension and cognitive impairment are common in Parkinson's disease (PD)
and significantly impair quality of life. Orthostatic hypotension and cognitive impairment …

Chronic liver disease in an ageing population

J Frith, D Jones, JL Newton - Age and ageing, 2009 - academic.oup.com
The prevalence of chronic liver disease is increasing in the elderly population. With a mostly
asymptomatic or non-specific presentation, these diseases may easily go undiagnosed …

Sex and age are determinants of the clinical phenotype of primary biliary cirrhosis and response to ursodeoxycholic acid

M Carbone, GF Mells, G Pells, MF Dawwas, JL Newton… - Gastroenterology, 2013 - Elsevier
BACKGROUND, & AIMS: Studies of primary biliary cirrhosis (PBC) phenotypes largely have
been performed using small and selected populations. Study size has precluded …

Non-alcoholic fatty liver disease in older people

J Frith, CP Day, E Henderson, AD Burt, JL Newton - Gerontology, 2009 - karger.com
Background: Non-alcoholic fatty liver disease (NAFLD) is principally a disease of middle and
old age. Previous studies reported it to be benign in old age, however more recent studies …

Development, validation, and evaluation of the PBC-40, a disease specific health related quality of life measure for primary biliary cirrhosis

A Jacoby, A Rannard, D Buck, N Bhala, JL Newton… - Gut, 2005 - gut.bmj.com
Background and aims: Study of health related quality of life (HRQOL) and the factors
responsible for its impairment in primary biliary cirrhosis (PBC) has, to date, been limited …

[PDF][PDF] Impact of primary biliary cirrhosis on perceived quality of life: the UK‐PBC national study

GF Mells, G Pells, JL Newton, AJ Bathgate… - …, 2013 - Wiley Online Library
Primary biliary cirrhosis (PBC) has a complex clinical phenotype, with debate about the
extent and specificity of frequently described systemic symptoms such as fatigue. The aim of …

Fatigue in non-alcoholic fatty liver disease (NAFLD) is significant and associates with inactivity and excessive daytime sleepiness but not with liver disease severity or …

JL Newton, DEJ Jones, E Henderson, L Kane, K Wilton… - Gut, 2008 - gut.bmj.com
Objective: To quantify fatigue in non-alcoholic fatty liver disease (NAFLD), to determine
whether perceived fatigue reflects impairment of physical function and to explore potential …

[PDF][PDF] Fatigue in primary biliary cirrhosis is associated with excessive daytime somnolence

JL Newton, GJ Gibson, M Tomlinson, K Wilton… - …, 2006 - Wiley Online Library
A significant proportion of patients with primary biliary cirrhosis (PBC) suffer from severe
fatigue. The aim of this study was to characterize patterns of daytime sleep in patients with …

Chronic inflammation is a feature of Achilles tendinopathy and rupture

SG Dakin, J Newton, FO Martinez, R Hedley… - British journal of sports …, 2018 - bjsm.bmj.com
Background Recent investigation of human tissue and cells from positional tendons such as
the rotator cuff has clarified the importance of inflammation in the development and …