Myostatin, insulin‐like growth factor‐1, and leukemia inhibitory factor mRNAs are upregulated in chronic human disuse muscle atrophy

KA Reardon, J Davis, RMI Kapsa… - Muscle & Nerve …, 2001 - Wiley Online Library
Human disuse muscle atrophy frequently accompanies orthopedic injury, arthritis, or bed
rest, and recovery is often incomplete despite current rehabilitation programs. We have …

Direct measurements of the coordination of lever arm swing and the catalytic cycle in myosin V

DV Trivedi, JM Muretta, AM Swenson… - Proceedings of the …, 2015 - National Acad Sciences
Myosins use a conserved structural mechanism to convert the energy from ATP hydrolysis
into a large swing of the force-generating lever arm. The precise timing of the lever arm …

DUF1220 copy number is linearly associated with increased cognitive function as measured by total IQ and mathematical aptitude scores

JM Davis, VB Searles, N Anderson, J Keeney… - Human genetics, 2015 - Springer
DUF1220 protein domains exhibit the greatest human lineage-specific copy number
expansion of any protein-coding sequence in the genome, and variation in DUF1220 copy …

Development and maturation of the fibrous components of the arterial roots in the mouse heart

R Richardson, L Eley, C Donald‐Wilson… - Journal of …, 2018 - Wiley Online Library
The arterial roots are important transitional regions of the heart, connecting the
intrapericardial components of the aortic and pulmonary trunks with their ventricular outlets …

Immunoglobulin genes expressed by B-lymphocytes infiltrating cervical carcinomas show evidence of antigen-driven selection

PM O'Brien, E Tsirimonaki, DW Coomber… - Cancer Immunology …, 2001 - Springer
Lymphocyte infiltration is often present in cervical cancer lesions, possibly reflecting an
ongoing (but ineffective) immune response to the tumour. B-lymphocytes are the …

Increased levels of leukemia inhibitory factor mRNA in muscular dystrophy and human muscle trauma

KA Reardon, RMI Kapsa, J Davis… - Muscle & Nerve …, 2000 - Wiley Online Library
Leukemia inhibitory factor (LIF) is an important muscle trauma factor both after crush injury
and in the mdx mouse dystrophy model. It is important to establish which growth factors have …

Early adenosine receptor activation ameliorates spinal cord reperfusion injury

TB Reece, CG Tribble, DO Okonkwo… - Journal of …, 2008 - journals.lww.com
Objectives Adenosine receptor activation at reperfusion has been shown to ameliorate
ischemia–reperfusion injury of the spinal cord, but the effects of therapy given in response to …

A case of massive thymolipoma

AK Gregory, CP Connery, F Resta-Flarer… - Journal of pediatric …, 1997 - Elsevier
A massive anterior mediastinal tumor was discovered in a 9-year-old girl with long-standing
symptoms of asthma. Preoperative computed tomography (CT) scan and magnetic …

Procedural dungeon generation for a 2D top-down game

M Weeks, J Davis - Proceedings of the 2022 ACM Southeast Conference, 2022 - dl.acm.org
This work examines solvability, difficulty, and engagement of procedurally generated content
for a 2D, top-down game. We adapt the A* algorithm to find a solution when there are keys …

In Situ isolation of immunoglobulin sequences expressed by single tumor-infiltrating B cells using laser-assisted microdissection

PM O'brien, DWM Millan, JA Davis… - Molecular …, 2005 - Springer
The isolation of fully human monoclonal antibodies (MAb) against tumor targets has to date
relied largely on combinatorial library-based antibody display techniques, which generally …