Tuberculosis continues to cause an unacceptably high toll of disease and death among
children worldwide, particularly in the wake of the HIV epidemic. Increased international …

Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-
TS) is a novel condition that was first reported in April, 2020. We aimed to develop a national …

Objective To undertake a systematic review of reviews of the prevalence of symptoms and
signs of COVID-19 in those aged under 20 years. Design Narrative systematic review of …

Importance In communities with high rates of coronavirus disease 2019, reports have
emerged of children with an unusual syndrome of fever and inflammation. Objectives To …

Between 7 and 25 May, 86 monkeypox cases were confirmed in the United Kingdom (UK).
Only one case is known to have travelled to a monkeypox virus (MPXV) endemic country …

patients still in the hospital (94 [37%]) at the end of follow-up. The multivariable Cox model
analysis showed that history of chronic pulmonary disease had the highest adjusted hazard …

Summary Background In April, 2020, clinicians in the UK observed a cluster of children with
unexplained inflammation requiring admission to paediatric intensive care units (PICUs). We …

Adenosine deaminases acting on RNA (ADARs) catalyze the hydrolytic deamination of
adenosine to inosine in double-stranded RNA (dsRNA) and thereby potentially alter the …

Aicardi-Goutières syndrome is a mendelian mimic of congenital infection and also shows
overlap with systemic lupus erythematosus at both a clinical and biochemical level. The …

Background The long-term sequelae of coronavirus disease 2019 (COVID-19) in children
remain poorly characterised. This study aimed to assess long-term outcomes in children …