[HTML][HTML] Moderate hypothermia to treat perinatal asphyxial encephalopathy
DV Azzopardi, B Strohm, AD Edwards… - … England Journal of …, 2009 - Mass Medical Soc
Background Whether hypothermic therapy improves neurodevelopmental outcomes in
newborn infants with asphyxial encephalopathy is uncertain. Methods We performed a …
newborn infants with asphyxial encephalopathy is uncertain. Methods We performed a …
Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop
Perinatal hypoxic-ischemic encephalopathy (HIE), a subset of neonatal encephalopathy, is
associated with high neonatal mortality and severe long-term neurologic morbidity. Until …
associated with high neonatal mortality and severe long-term neurologic morbidity. Until …
[HTML][HTML] Numerical modeling of temperature distributions within the neonatal head
GMJ Van Leeuwen, JW Hand, JJW Lagendijk… - Pediatric …, 2000 - nature.com
Introduction of hypothermia therapy as a neuroprotection therapy after hypoxia-ischemia in
newborn infants requires appraisal of cooling methods. In this numerical study thermal …
newborn infants requires appraisal of cooling methods. In this numerical study thermal …
Pharmacokinetics of melatonin in preterm infants
NM Merchant, DV Azzopardi, AF Hawwa… - British journal of …, 2013 - Wiley Online Library
Aims Preterm infants are deprived of the normal intra‐uterine exposure to maternal
melatonin and may benefit from replacement therapy. We conducted a pharmacokinetic …
melatonin and may benefit from replacement therapy. We conducted a pharmacokinetic …
[HTML][HTML] Punctate white matter lesions associated with altered brain development and adverse motor outcome in preterm infants
N Tusor, MJ Benders, SJ Counsell, P Nongena… - Scientific reports, 2017 - nature.com
Preterm infants who develop neurodevelopmental impairment do not always have
recognized abnormalities on cerebral ultrasound, a modality routinely used to assess …
recognized abnormalities on cerebral ultrasound, a modality routinely used to assess …
Confidence in the prediction of neurodevelopmental outcome by cranial ultrasound and MRI in preterm infants
P Nongena, A Ederies, DV Azzopardi… - Archives of Disease in …, 2010 - fn.bmj.com
In one major study, images with only grade 1 or 2 IVH showed a low risk of abnormal
neuromotor development with narrow confidence limits: PPV 6%(95% CI 4% to 9%). 9 …
neuromotor development with narrow confidence limits: PPV 6%(95% CI 4% to 9%). 9 …
Mild controlled hypothermia in preterm neonates with advanced necrotizing enterocolitis
OBJECTIVES: Necrotizing enterocolitis (NEC) with multiple organ dysfunction syndrome
(MODS) carries significant morbidity and mortality. There is extensive experimental evidence …
(MODS) carries significant morbidity and mortality. There is extensive experimental evidence …
Neuroprotection for perinatal hypoxic ischemic encephalopathy in low-and middle-income countries
M Tagin, H Abdel-Hady, S ur Rahman… - The Journal of …, 2015 - jpeds.com
Mohamed Tagin, MB, BCh1, Hesham Abdel-Hady, PhD2, Sajjad ur Rahman, MBBS, DCH,
MCPS, FCPS, FRCPCH3, 4, Denis V. Azzopardi, FRCPCH5, and Alistair J. Gunn, MBChB …
MCPS, FCPS, FRCPCH3, 4, Denis V. Azzopardi, FRCPCH5, and Alistair J. Gunn, MBChB …
Patterns of brain injury and outcome in term neonates presenting with postnatal collapse
A Foran, C Cinnante, A Groves, DV Azzopardi… - Archives of Disease in …, 2009 - fn.bmj.com
Objective: To document perinatal events, brain imaging, neurophysiology and clinical
outcome in term infants with early postnatal collapse (PNC). Design: Tertiary referral centre …
outcome in term infants with early postnatal collapse (PNC). Design: Tertiary referral centre …
[BOOK][B] Neonatal neural rescue: a clinical guide
Worldwide more than one million babies die annually from perinatal asphyxia and its
associated complications such as neonatal encephalopathy–one of the major causes of …
associated complications such as neonatal encephalopathy–one of the major causes of …