Quantitative evaluation of Escherichia coli host strains for tolerance to cytosine methylation in plasmid and phage recombinants
DM Woodcock, PJ Crowther, J Doherty… - Nucleic acids …, 1989 - academic.oup.com
Many strains of E. coli K12 restrict DNA containing cytosine methylation such as that present
in plant and animal genomes. Such restriction can severely inhibit the efficiency of cloning …
in plant and animal genomes. Such restriction can severely inhibit the efficiency of cloning …
New product development in British SMEs
DJ Woodcock, SP Mosey, TBW Wood - European Journal of …, 2000 - emerald.com
Reports the efforts of six British small and medium enterprises (SMEs) to enhance their new
product development (NPD) capabilities. Finds a strong recognition by managers of “the …
product development (NPD) capabilities. Finds a strong recognition by managers of “the …
A mechanism for sustained groundwater pressure changes induced by distant earthquakes
EE Brodsky, E Roeloffs, D Woodcock… - Journal of …, 2003 - Wiley Online Library
Large, sustained well water level changes (> 10 cm) in response to distant (more than
hundreds of kilometers) earthquakes have proven enigmatic for over 30 years. Here we use …
hundreds of kilometers) earthquakes have proven enigmatic for over 30 years. Here we use …
[HTML][HTML] Spatially resolved clonal copy number alterations in benign and malignant tissue
A Erickson, M He, E Berglund, M Marklund… - Nature, 2022 - nature.com
Defining the transition from benign to malignant tissue is fundamental to improving early
diagnosis of cancer. Here we use a systematic approach to study spatial genome integrity in …
diagnosis of cancer. Here we use a systematic approach to study spatial genome integrity in …
[HTML][HTML] Dynamic analysis of stochastic transcription cycles
In individual mammalian cells the expression of some genes such as prolactin is highly
variable over time and has been suggested to occur in stochastic pulses. To investigate the …
variable over time and has been suggested to occur in stochastic pulses. To investigate the …
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets
Prostate cancer represents a substantial clinical challenge because it is difficult to predict
outcome and advanced disease is often fatal. We sequenced the whole genomes of 112 …
outcome and advanced disease is often fatal. We sequenced the whole genomes of 112 …
Reversal of multidrug resistance by surfactants
DM Woodcock, ME Linsenmeyer, G Chojnowski… - British Journal of …, 1992 - nature.com
Cremophor EL, a pharmacologically inactive solubilising agent, has been shown to reverse
multidrug resistance (MDR). Using flow cytometric evaluation of equilibrium intracellular …
multidrug resistance (MDR). Using flow cytometric evaluation of equilibrium intracellular …
Assessing risk factors for transmission of infection
JS Koopman, IM Longini Jr, JA Jacquez… - American Journal of …, 1991 - academic.oup.com
Commonly used measures of effect, such as risk ratios and odds ratios, may be quite biased
when used to assess the effect of factors that alter transmission risks given exposure to …
when used to assess the effect of factors that alter transmission risks given exposure to …
The widespread occurrence of negative thermal expansion in zeolitesBasis of a presentation given at Materials Discussion No. 3, 26–29 September, 2000, University …
P Lightfoot, DA Woodcock, MJ Maple… - Journal of materials …, 2001 - pubs.rsc.org
Powder X-ray and neutron diffraction studies of the calcined siliceous zeolites ITQ-7, ITQ-9
and CIT-5, and the aluminophosphates AlPO4-31 and Mg-doped AlPO4-17 have been …
and CIT-5, and the aluminophosphates AlPO4-31 and Mg-doped AlPO4-17 have been …
[HTML][HTML] Asymmetric methylation in the hypermethylated CpG promoter region of the human L1 retrotransposon
DM Woodcock, CB Lawler, ME Linsenmeyer… - Journal of Biological …, 1997 - ASBMB
We have investigated the function and sequence specificity of DNA methylation in the
hypermethylated CpG island promoter region of the endogenous human LINE-1 (L1) …
hypermethylated CpG island promoter region of the endogenous human LINE-1 (L1) …