Patent ductus arteriosus (PDA) is a common diagnosis among extremely premature infants,
especially in those with lung disease. Treatments are often used to close the PDA. Despite …

Bronchopulmonary dysplasia (BPD) is the most common, serious sequela of premature
birth. Inflammation is a major contributor to the pathogenesis of BPD. Often initiated by a …

In preterm infants, patency of the ductus arteriosus may represent a normal physiologic
adaptation to allow shunting from either systemic-to-pulmonary circulation (eg, in the first …

Rationale: Benefits of identifying risk factors for bronchopulmonary dysplasia in extremely
premature infants include providing prognostic information, identifying infants likely to …

Background The safety and efficacy of early, low-dose, prolonged therapy with inhaled nitric
oxide in premature newborns with respiratory failure are uncertain. Methods We performed a …

Background Preterm birth remains a common cause of neonatal mortality, with a
disproportionately high burden in low-income and middle-income countries. Meta-analyses …

Objective. To identify risk factors for chronic lung disease (CLD) in a population-based
cohort of very low birth weight infants, born in an era of surfactant usage. We specifically …

Background Of the 3.7 million neonatal deaths and 3.3 million stillbirths each year, 98%
occur in developing countries. An evaluation of community-based interventions designed to …

OBJECTIVE: Improvement in survival of extremely premature infants over the past several
decades has resulted in an increase in the number of infants with chronic lung disease …

BACKGROUND. Chronic lung disease is one of the most frequent and serious complications
of premature birth. Because mechanical ventilation is a major risk factor for chronic lung …