Background Survivors of infant group B streptococcal (GBS) disease are at risk of
neurodevelopmental impairment (NDI), a burden not previously systematically quantified …

In the last two decades, the global community has made significant progress in saving the
lives of children< 5 y of age. However, these advances are failing to help all children to …

Perinatal insults are a leading cause of infant mortality and amongst survivors are frequently
associated with neurocognitive impairment, cerebral palsy (CP), and seizure disorders. The …

Background We aimed to provide the first comprehensive estimates of the burden of group B
Streptococcus (GBS), including invasive disease in pregnant and postpartum women, fetal …

Background In low and middle-income settings, where access to support and rehabilitation
services for children with disabilities are often lacking, the evidence base for community …

Improving maternal, newborn, and child health is central to Sustainable Development Goal
targets for 2030, requiring acceleration especially to prevent 5.6 million deaths around the …

Background COVID-19 is disrupting health services for mothers and newborns, particularly
in low-and middle-income countries (LMIC). Preterm newborns are particularly vulnerable …

Objective Neonatal encephalopathy (NE) is the third leading cause of child mortality.
Preclinical studies suggest infection and inflammation can sensitise or precondition the …

Background Neonatal encephalopathy (NE) is a leading cause of child mortality and longer-
term impairment. Infection can sensitize the newborn brain to injury; however, the role of …

Background In neonatal encephalopathy (NE), infectious co-morbidity is difficult to diagnose
accurately, but may increase the vulnerability of the developing brain to hypoxia-ischemia …