Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association

RA Insel, JL Dunne, MA Atkinson, JL Chiang… - Diabetes …, 2015 - Am Diabetes Assoc
Insights from prospective, longitudinal studies of individuals at risk for developing type 1
diabetes have demonstrated that the disease is a continuum that progresses sequentially at …

[HTML][HTML] Latent autoimmune diabetes in adults (LADA) should be less latent

S Fourlanos, F Dotta, CJ Greenbaum, JP Palmer… - Diabetologia, 2005 - Springer
Abstract 'Latent autoimmune diabetes in adults'(LADA) is the term coined to describe adults
who have a slowly progressive form of autoimmune or type 1 diabetes that can be treated …

Screening for type 1 diabetes in the general population: a status report and perspective

…, C Dayan, C Geno Rasmussen, C Greenbaum… - Diabetes, 2022 - Am Diabetes Assoc
Most screening programs to identify individuals at risk for type 1 diabetes have targeted
relatives of people living with the disease to improve yield and feasibility. However,∼ 90 …

Improvement in outcomes of clinical islet transplantation: 1999–2010

…, A Naji, PJ O'Connell, C Greenbaum… - Diabetes …, 2012 - Am Diabetes Assoc
OBJECTIVE To describe trends of primary efficacy and safety outcomes of islet
transplantation in type 1 diabetes recipients with severe hypoglycemia from the …

Fall in C-peptide during first 2 years from diagnosis: evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data

CJ Greenbaum, CA Beam, D Boulware, SE Gitelman… - Diabetes, 2012 - Am Diabetes Assoc
Interpretation of clinical trials to alter the decline in β-cell function after diagnosis of type 1
diabetes depends on a robust understanding of the natural history of disease. Combining …

[HTML][HTML] Rituximab, B-lymphocyte depletion, and preservation of beta-cell function

MD Pescovitz, CJ Greenbaum… - … England Journal of …, 2009 - Mass Medical Soc
Background The immunopathogenesis of type 1 diabetes mellitus is associated with T-
lymphocyte autoimmunity. However, there is growing evidence that B lymphocytes play a …

Mother–infant affect synchrony as an antecedent of the emergence of self-control.

R Feldman, CW Greenbaum… - Developmental …, 1999 - psycnet.apa.org
This study examined relations between mother–infant affect synchrony and the emergence
of children's self-control. Mother–infant face-to-face play and infant difficult temperament …

[HTML][HTML] An anti-CD3 antibody, teplizumab, in relatives at risk for type 1 diabetes

KC Herold, BN Bundy, SA Long… - … England Journal of …, 2019 - Mass Medical Soc
Background Type 1 diabetes is a chronic autoimmune disease that leads to destruction of
insulin-producing beta cells and dependence on exogenous insulin for survival. Some …

Identification of tissue-specific cell death using methylation patterns of circulating DNA

R Lehmann-Werman, D Neiman… - Proceedings of the …, 2016 - National Acad Sciences
Minimally invasive detection of cell death could prove an invaluable resource in many
physiologic and pathologic situations. Cell-free circulating DNA (cfDNA) released from dying …

C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve β-cell function: report of an ADA workshop, 21–22 October 2001

JP Palmer, GA Fleming, CJ Greenbaum, KC Herold… - Diabetes, 2004 - Am Diabetes Assoc
The underlying cause of type 1 diabetes, loss of β-cell function, has become the therapeutic
target for a number of interventions in patients with type 1 diabetes. Even though insulin …