Horses were domesticated from the Eurasian steppes 5,000–6,000 years ago. Since then,
the use of horses for transportation, warfare, and agriculture, as well as selection for desired …

Intense selective pressures applied over short evolutionary time have resulted in
homogeneity within, but substantial variation among, horse breeds. Utilizing this population …

The molecular analysis of genes influencing human height has been notoriously difficult.
Genome-wide association studies (GWAS) for height in humans based on tens of thousands …

During fetal development neural-crest-derived melanoblasts migrate across the entire body
surface and differentiate into melanocytes, the pigment-producing cells. Alterations in this …

White coat color has been a highly valued trait in horses for at least 2,000 years. Dominant
white (W) is one of several known depigmentation phenotypes in horses. It shows …

Osteogenesis imperfecta (OI) is a hereditary disease occurring in humans and dogs. It is
characterized by extremely fragile bones and teeth. Most human and some canine OI cases …

Leopard complex spotting is a group of white spotting patterns in horses caused by an
incompletely dominant gene (LP) where homozygotes (LP/LP) are also affected with …

White coat colour in horses is inherited as a monogenic autosomal dominant trait showing a
variable expression of coat depigmentation. Mutations in the KIT gene have previously been …

Background To date, genome-scale analyses in the domestic horse have been limited by
suboptimal single nucleotide polymorphism (SNP) density and uneven genomic coverage of …

Coat color dilution in several breeds of dog is characterized by a specific pigmentation
phenotype and sometimes accompanied by hair loss and recurrent skin inflammation, the so …