User profiles for "author:A Schulze"
Almut SchulzeGerman Cancer Research Center Verified email at dkfz-heidelberg.de Cited by 20627 |
[PDF][PDF] Cellular fatty acid metabolism and cancer
Cancer cells often have characteristic changes in metabolism. Cellular proliferation, a
common feature of all cancers, requires fatty acids for synthesis of membranes and signaling …
common feature of all cancers, requires fatty acids for synthesis of membranes and signaling …
How cancer metabolism is tuned for proliferation and vulnerable to disruption
Cancer metabolism has received a substantial amount of interest over the past decade. The
advances in analytical tools have, along with the rapid progress of cancer genomics …
advances in analytical tools have, along with the rapid progress of cancer genomics …
Lipid metabolism in cancer
Lipids form a diverse group of water‐insoluble molecules that include triacylglycerides,
phosphoglycerides, sterols and sphingolipids. They play several important roles at cellular …
phosphoglycerides, sterols and sphingolipids. They play several important roles at cellular …
FSP1 is a glutathione-independent ferroptosis suppressor
Ferroptosis is an iron-dependent form of necrotic cell death marked by oxidative damage to
phospholipids,. To date, ferroptosis has been thought to be controlled only by the …
phospholipids,. To date, ferroptosis has been thought to be controlled only by the …
[PDF][PDF] SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth
…, M Wu, S Leevers, JR Griffiths, YL Chung, A Schulze - Cell metabolism, 2008 - cell.com
Cell growth (accumulation of mass) needs to be coordinated with metabolic processes that
are required for the synthesis of macromolecules. The PI3-kinase/Akt signaling pathway …
are required for the synthesis of macromolecules. The PI3-kinase/Akt signaling pathway …
Optical investigation of Bloch oscillations in a semiconductor superlattice
…, JE Cunningham, T Meier, G Von Plessen, A Schulze… - Physical Review B, 1992 - APS
We report the study of optical dephazing of Wannier-Stark ladder excitations in a
semiconductor superlattice by means of transient degenerate four-wave mixing. We observe …
semiconductor superlattice by means of transient degenerate four-wave mixing. We observe …
The multifaceted roles of fatty acid synthesis in cancer
F Röhrig, A Schulze - Nature reviews cancer, 2016 - nature.com
Lipid metabolism, in particular the synthesis of fatty acids (FAs), is an essential cellular
process that converts nutrients into metabolic intermediates for membrane biosynthesis …
process that converts nutrients into metabolic intermediates for membrane biosynthesis …
[PDF][PDF] Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
…, EO Aboagye, SE Critchlow, MJO Wakelam, A Schulze… - Cancer cell, 2015 - cell.com
A functional genomics study revealed that the activity of acetyl-CoA synthetase 2 (ACSS2)
contributes to cancer cell growth under low-oxygen and lipid-depleted conditions …
contributes to cancer cell growth under low-oxygen and lipid-depleted conditions …
[PDF][PDF] Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation
An in vivo model of antiangiogenic therapy allowed us to identify genes upregulated by
bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of …
bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of …
Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development
An increased rate of lipid synthesis in cancerous tissues has long been recognised as an
important aspect of the rewired metabolism of transformed cells. However, the contribution of …
important aspect of the rewired metabolism of transformed cells. However, the contribution of …