[HTML][HTML] rhIGF-1/rhIGFBP-3 in preterm infants: a phase 2 randomized controlled trial
Objective To investigate recombinant human insulin-like growth factor 1 complexed with its
binding protein (rhIGF-1/rhIGFBP-3) for the prevention of retinopathy of prematurity (ROP) …
binding protein (rhIGF-1/rhIGFBP-3) for the prevention of retinopathy of prematurity (ROP) …
Diagnosing and preventing hearing loss in the genomic age
…, LP Molina-Ramírez, IA Bruce, A Mahaveer… - Trends in …, 2019 - journals.sagepub.com
Over the past two decades, significant technological advances have facilitated the
identification of hundreds of genes associated with hearing loss. Variants in many of these …
identification of hundreds of genes associated with hearing loss. Variants in many of these …
Rapid point-of-care genotyping to avoid aminoglycoside-induced ototoxicity in neonatal intensive care
JH McDermott, A Mahaveer, RA James, N Booth… - JAMA …, 2022 - jamanetwork.com
Importance Aminoglycosides are commonly prescribed antibiotics used for the treatment of
neonatal sepsis. TheMT-RNR1m. 1555A> G variant predisposes to profound …
neonatal sepsis. TheMT-RNR1m. 1555A> G variant predisposes to profound …
[HTML][HTML] Exclusively breastmilk‐fed preterm infants are at high risk of developing subclinical vitamin K deficiency despite intramuscular prophylaxis at birth
…, DJ Card, A Nichols, V Ponnusamy, A Mahaveer… - Journal of Thrombosis …, 2022 - Elsevier
Background There is near‐global consensus that all newborns be given parenteral vitamin
K 1 (VK 1) at birth as prophylaxis against VK deficiency bleeding (VKDB). Breastmilk has a …
K 1 (VK 1) at birth as prophylaxis against VK deficiency bleeding (VKDB). Breastmilk has a …
Increasing early protein intake is associated with a reduction in insulin‐treated hyperglycemia in very preterm infants
A Mahaveer, C Grime, C Morgan - Nutrition in clinical practice, 2012 - Wiley Online Library
Background: Impaired early protein intake in very preterm infants contributes to early growth
failure and may affect long‐term neurocognitive development. The authors have previously …
failure and may affect long‐term neurocognitive development. The authors have previously …
Optimised versus standard dosing of vancomycin in infants with Gram-positive sepsis (NeoVanc): a multicentre, randomised, open-label, phase 2b, non-inferiority trial
…, E Baraldi, A Dotta, ML Ilmoja, A Mahaveer… - The Lancet Child & …, 2022 - thelancet.com
Background Vancomycin is the most widely used antibiotic for neonatal Gram-positive
sepsis, but clinical outcome data of dosing strategies are scarce. The NeoVanc programme …
sepsis, but clinical outcome data of dosing strategies are scarce. The NeoVanc programme …
Pharmacogenetics to avoid loss of hearing (PALOH) trial: a protocol for a prospective observational implementation trial
JH McDermott, R Mahood, D Stoddard, A Mahaveer… - BMJ open, 2021 - bmjopen.bmj.com
Introduction In conjunction with a beta-lactam, aminoglycosides are the first-choice antibiotic
for empirical treatment of sepsis in the neonatal period. The m. 1555A> G variant …
for empirical treatment of sepsis in the neonatal period. The m. 1555A> G variant …
[HTML][HTML] How to know when little kidneys are in trouble: a review of current tools for diagnosing AKI in neonates
RE Evans, J Peterson, JJ Kim, A Mahaveer - Frontiers in Pediatrics, 2023 - frontiersin.org
Due to a plethora of risk factors, including prematurity, neonates are at risk for acute kidney
injury (AKI) and, once established, AKI is associated with poor outcomes. The most widely …
injury (AKI) and, once established, AKI is associated with poor outcomes. The most widely …
Exploring NICU nurses' views of a novel genetic point‐of‐care test identifying neonates at risk of antibiotic‐induced ototoxicity: A qualitative study
…, JH Mcdermott, D Stoddard, A Mahaveer… - Journal of Advanced …, 2024 - Wiley Online Library
Aim To explore the views of neonatal intensive care nursing staff on the deliverability of a
novel genetic point‐of‐care test detecting a genetic variant associated with antibiotic …
novel genetic point‐of‐care test detecting a genetic variant associated with antibiotic …
Perinatal Optimisation for Periviable Birth and Outcomes: A 4-Year Network Analysis (2018-2021) across a change in national guidance
…, DM Smith, E Johnstone, A Mahaveer - Frontiers in …, 2024 - frontiersin.org
The British Association of Perinatal Medicine (BAPM) released their revised framework for
extremely preterm infant management in 2019. This revised framework promotes …
extremely preterm infant management in 2019. This revised framework promotes …