In the few past years the Netherlands Centre for Monitoring of Adverse Reactions to Drugs and the Teratology Information Service of the National Institute of Public Health and Environmental Protection received several reports of neurological symptoms in neonates, which were the result of maternal treatment with psychotropic drugs during late pregnancy. The results are summarised in this article. The neonatal symptoms (withdrawal symptoms, 'floppy infant syndrome' and extrapyramidal syndrome) are described together with the psychotropic drugs which may cause them.