Evidence based management guidelines for the detection and treatment of congenital CMV

S Kadambari; E J Williams; S Luck; P D Griffiths; M Sharland

doi:10.1016/j.earlhumdev.2011.08.021

Evidence based management guidelines for the detection and treatment of congenital CMV

Early Hum Dev. 2011 Nov;87(11):723-8. doi: 10.1016/j.earlhumdev.2011.08.021. Epub 2011 Sep 29.

Authors

S Kadambari¹, E J Williams, S Luck, P D Griffiths, M Sharland

Affiliation

¹ Paediatric Infectious Diseases Unit, St George's University of London, Cranmer Terrace, London, United Kingdom. skadamba@sgul.ac.uk

PMID: 21962770
DOI: 10.1016/j.earlhumdev.2011.08.021

Abstract

CMV is the most common congenital infection in newborns worldwide. Congenital CMV causes sensorineural hearing loss in a significant proportion of infected newborns, while the majority of newborns are asymptomatic. In the last three years there have been significant advances in the diagnosis and treatment of congenital CMV. We have developed practical evidence based guidelines for the management of congenital CMV.

Publication types

Practice Guideline

MeSH terms

Algorithms
Cytomegalovirus / isolation & purification
Cytomegalovirus / pathogenicity
Cytomegalovirus Infections / congenital*
Cytomegalovirus Infections / diagnosis*
Cytomegalovirus Infections / drug therapy*
Cytomegalovirus Infections / urine
Cytomegalovirus Infections / virology
Drug Monitoring / standards
Evidence-Based Medicine*
Ganciclovir / analogs & derivatives
Ganciclovir / pharmacology
Hearing Loss, Sensorineural / congenital
Hearing Loss, Sensorineural / virology
Humans
Infant, Newborn
Neonatal Screening / methods
Neonatal Screening / standards*
Saliva / virology
Sensitivity and Specificity
Valganciclovir
Viral Load / drug effects

Substances

Valganciclovir
Ganciclovir