[Randomized trail of nasal synchronized intermittent mandatory ventilation compared with nasal continuous positive airway pressure in preterm infants with respiratory distress syndrome]

Zhongguo Dang Dai Er Ke Za Zhi. 2010 Jul;12(7):524-6.
[Article in Chinese]

Abstract

Objective: To compare the efficacy of nasal synchronized intermittent mandatory ventilation (nSIMV) and nasal continuous positive airway pressure (nCPAP) in preterm infants with respiratory distress syndrome (RDS).

Methods: Fifty preterm infants with RDS who received pulmonary surfactant were randomized to nSIMV and nCPAP groups after extubation. Clinical signs, symptoms and blood gas results following nSIMV or nCPAP were compared in the two groups.

Results: Compared with the nCPAP group, the nSIMV group had a lower incidence of failure respiratory support (24% vs 60%; P<0.05), a lower incidence of hypercarbonia (12% vs 40%; P<0.05) and a lower incidence of hypoxia (24% vs 36%; P<0.05).

Conclusions: nSIMV is more effective in respiratory support in preterm infants with RDS.

Publication types

  • Comparative Study
  • English Abstract
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Continuous Positive Airway Pressure / methods*
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Intermittent Positive-Pressure Ventilation / methods*
  • Respiratory Distress Syndrome, Newborn / therapy*