Prolonged time to pregnancy is associated with a greater risk of adverse outcomes

Kaisa Raatikainen; Maija Harju; Maritta Hippeläinen; Seppo Heinonen

doi:10.1016/j.fertnstert.2009.10.058

Prolonged time to pregnancy is associated with a greater risk of adverse outcomes

Fertil Steril. 2010 Aug;94(3):1148-51. doi: 10.1016/j.fertnstert.2009.10.058. Epub 2009 Dec 11.

Authors

Kaisa Raatikainen¹, Maija Harju, Maritta Hippeläinen, Seppo Heinonen

Affiliation

¹ Department of Obstetrics and Gynecology, Kuopio University Hospital, and Faculty of Medicine, Kuopio University, Kuopio, Finland. kaisa.e.raatikainen@kuh.fi

PMID: 20004381
DOI: 10.1016/j.fertnstert.2009.10.058

Abstract

Births with known time to pregnancy (TTP) during the period 1989-2007 (n=17,114) were analyzed to investigate associations between TTP and pregnancy outcome among couples that conceived spontaneously. The adjusted odds ratio (95% confidence interval) for poor neonatal health, including low Apgar score, low umbilical vein pH, and need for neonatal intensive care, was 1.51 (1.09-2.09) in women who had a TTP of 25-36 months and 1.60 (1.18-2.19) in women who had a TTP of >or=37 months compared with women with a TTP of 0-6 months.

MeSH terms

Apgar Score
Birth Weight / physiology
Female
Fertility / physiology
Humans
Infant, Newborn
Infant, Newborn, Diseases / epidemiology
Pregnancy
Pregnancy Complications / epidemiology
Pregnancy Outcome / epidemiology*
Regression Analysis
Reproductive Techniques, Assisted / statistics & numerical data
Risk
Surveys and Questionnaires
Time Factors