Behavioral outcome in children with a history of neonatal encephalopathy following perinatal asphyxia

J Pediatr Psychol. 2010 Apr;35(3):286-95. doi: 10.1093/jpepsy/jsp049. Epub 2009 Jun 19.

Abstract

Objective: To examine the effects of mild and moderate neonatal encephalopathy (NE) on behavioral functioning, and prevalence of psychiatric diagnoses at 9-10 years.

Methods: The Child Behavior Checklist (CBCL), Teacher's Report Form (TRF), Diagnostic Interview Schedule for Children IV (DISC-IV), and the Children's Social Behavior Questionnaire (CSBQ) were used to assess behavioral outcome of 34 children with mild NE, 47 children with moderate NE, and 53 typically developing controls.

Results: Both children with mild and moderate NE showed more problematic behaviors than controls, which are related to a diversity of behavioral domains: elevated rates of social problems, anxiety and depression, attention regulation problems, and thought problems. No group differences were found in percentages of children with a DISC-IV (DSM-IV) classification.

Conclusions: NE has a mildly negative effect on behavioral functioning, but does not lead to elevated levels or specific patterns of developmental psychopathology.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asphyxia Neonatorum / complications*
  • Asphyxia Neonatorum / epidemiology*
  • Child
  • Comorbidity
  • Female
  • Humans
  • Hypoxia-Ischemia, Brain / epidemiology*
  • Hypoxia-Ischemia, Brain / etiology*
  • Infant, Newborn
  • Male
  • Prevalence
  • Social Behavior Disorders / epidemiology*
  • Surveys and Questionnaires