Am J Perinatol 2002; 19(2): 081-086
DOI: 10.1055/s-2002-23558
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Contribution of Elective Delivery to Severe Respiratory Distress at Term

Joseph R. Wax1 , Victor Herson3 , Eva Carignan1 , Jeffrey Mather2 , Charles J. Ingardia1
  • 1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Hartford Hospital
  • 2Department of Research, Hartford Hospital
  • 3Division of Neonatology, Connecticut Children's Medical Center, Hartford, Connecticut
Further Information

Publication History

Publication Date:
02 April 2002 (online)

ABSTRACT

We sought to determine the contribution of elective delivery to severe respiratory distress syndrome (RDS) on a weekly basis from 37-40 weeks' gestation. Chart reviews confirmed gestational age, delivery reason, and primary diagnosis of all inborn neonates with RDS requiring mechanical ventilation delivered at 37 0/7-40 6/7 weeks' gestation from 1/1/90-12/31/99. Exclusion criteria were sepsis, pneumonia, meconium aspiration, asphyxia, pulmonary hemorrhage, hydrops, chromosomal abnormality, or congenital malformations affecting respiration. Thirty-five thousand and thirty-one deliveries occurred from 37 0/7-40 6/7 weeks; 18 (0.05%) had RDS requiring mechanical ventilation. Nine infants delivered at 37 0/7-37 6/7 weeks, (OR for RDS = 38.5; 95% CI = 8.3, 178.3), seven delivered at 38 0/7-38 6/7 weeks, (OR for RDS = 13.3; 95% CI = 2.8, 64.0), and two delivered at 39 0/7-40 6/7 weeks. Six of 18 infants were electively delivered without documented lung maturity. Infants born at 37 0/7-38 6/7 weeks are at significantly increased risk for severe RDS. One third of RDS cases were potentially avoidable.

REFERENCES

  • 1 Chervenak F A, Herslinger R, Freedman R, Lamastra P. Current perspective on iatrogenic neonatal respiratory distress syndrome.  J Reprod Med . 1986;  31 53-57
  • 2 Parilla B V, Dooley S L, Jansen R D, Socol M L. Iatrogenic respiratory distress syndrome following elective repeat cesarean delivery.  Obstet Gynecol . 1993;  83 392-395
  • 3 Goldenberg R L, Nelson K. Iatrogenic respiratory distress syndrome.  Am J Obstet Gynecol . 1975;  123 617-620
  • 4 Hack M, Fanaroff A A, Klaus M H, Mendelawitz B D, Merkatz I R. Neonatal respiratory distress following elective delivery: a preventable disease?.  Am J Obstet Gynecol . 1976;  126 43-47
  • 5 Morrison J J, Rennie J M, Milton P J. Neonatal respiratory morbidity and mode of delivery at term: influence of timing of elective cesarean section.  Br J Obstet Gynaecol . 1995;  102 101-106
  • 6 Madar J, Richmond S, Hey E. Surfactant-deficient respiratory distress after elective delivery at ``term''.  Acta Paediatr . 1999;  88 1244-1248
  • 7 American College of Obstetricians and Gynecologists. Assessment of fetal lung maturity.  ACOG Education Bulletin no. 230. Washington, DC: American College of Obstetricians and Gynecologists. November 1996; 
  • 8 Bowers S K, MacDonald H M, Shapiro E D. Prevention of iatrogenic neonatal respiratory distress syndrome: elective repeat cesarean section and spontaneous labor.  Am J Obstet Gynecol . 1982;  143 186-189
  • 9 European Congress of Perinatal Medicine. Working party to discuss nomenclature based on gestational age and birthweight.  Arch Dis Child . 1970;  45 730
  • 10 Cunningham F G, MacDonald P C, Gant N F, Leveno K J, Gilstrap L C. Williams Obstetrics.  19th ed. Norwalk, CT: Appleton & Lange 1993: 2
  • 11 Curet L B, Zachman R D, Rao A V, Poole W K, Morrison J, Burkett G. Effect of mode of delivery on incidence of respiratory distress syndrome.  Int J Gynecol Obstet . 1988;  27 165-170
  • 12 Nielsen T F, Hokegard K H. The incidence of acute neonatal respiratory disorders in relation to mode of delivery.  Acta Obstet Gynecol Scand . 1984;  63 109-114
  • 13 Schreiner R L, Stevens D C, Smith W L, Lemons J A, Golichowski A M, Padilla L M. Respiratory distress following elective repeat cesarean section.  Am J Obstet Gynecol . 1982;  143 689-692
  • 14 Brown M J, Oliver R E, Ramsden C A. Effects of adrenaline and of spontaneous labour on the secretion and absorption of lung fluid in the foetal lamb.  J Physiol . 1983;  344 137-152
  • 15 Irestedt L, Lagercrantz H, Hjemdahl P, Hagnevik K, Belfrage P. Fetal and maternal plasma cathecholamine levels at elective cesarean section under general and epidural anesthesia versus vaginal delivery.  Am J Obstet Gynecol . 1982;  142 1004-1010
  • 16 Marino P A, Roney S A. The effect of labor on surfactant secretion in newborn lung slices.  Biochem Biophys Acta . 1981;  664 389
  • 17 Bibby J G, Brunt J D, Hodgson H. Prostaglandins in umbilical plasma at elective cesarean section.  Br J Obstet Gynaecol . 1979;  86 282-284
  • 18 Flaksman R J, Vollman J H, Benfield D G. Iatrogenic prematurity due to elective termination of the uncomplicated pregnancy: a major perinatal health care problem.  Am J Obstet Gynecol . 1978;  132 885-888
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