Neuropediatrics 2010; 41(6): 241-245
DOI: 10.1055/s-0030-1270479
Original Article

© Georg Thieme Verlag KG Stuttgart · New York

Absent Cyclicity on aEEG within the First 24 h is Associated with Brain Damage in Preterm Infants

H. Kidokoro1 , 2 , T. Kubota1 , N. Hayashi1 , 2 , M. Hayakawa2 , K. Takemoto1 , Y. Kato1 , A. Okumura3
  • 1Department of Pediatrics, Anjo Kosei Hospital, Anjo, Japan
  • 2Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan
  • 3Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan
Further Information

Publication History

received 06.04.2010

accepted 16.12.2010

Publication Date:
28 March 2011 (online)

Abstract

Objective: Our aim was to clarify the relationship between amplitude-integrated electroencephalographic (aEEG) findings before 24 h of age in preterm infants and neurodevelopmental outcome.

Design: 12 infants born between 27 and 32 weeks of gestation were eligible. The recordings of aEEG and conventional EEG were started within 12 h after birth. The background aEEG findings were evaluated and classified. Additionally, we evaluated the absence or presence of changes on the lower border of the aEEG.

Results: All infants had discontinuous normal voltage background on aEEG, corresponding to decreased or normal continuity on conventional EEG. Cyclicity on aEEG was seen in 8 of 12 infants within 24 h of age, and all of these infants had favourable outcomes. Cyclicity on aEEG was not recognized in 4 infants. 3 of the 4 infants with absent cyclicity had abnormal neurodevelopmental outcomes at 12 months. One of these infants had intraventricular haemorrhage (grade 2) with delayed development, and 2 had cystic periventricular leukomalacia followed by spastic diplegia.

Conclusion: Absent cyclicity on aEEG within 24 h of age was associated with poor outcome in preterm infants.

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Correspondence

Hiroyuki KidokoroMD 

Department of Pediatrics

Nagoya University Graduate

School of Medicine

65 Tsurumai-cho Showa-ku

466-8550 Nagoya

Japan

Phone: +81/52/741 2111

Fax: +81/52/741 2974

Email: kidokorowu@yahoo.co.jp

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