Case ReportsPrimary pulmonary rhabdomyosarcoma arising within cystic adenomatoid malformation: A case report and review of the literature*
Section snippets
Case report
A 13-month old boy with a 3-month history of persistent cough, fever, and dyspnea was admitted to a pediatric surgical center for a left pleural effusion (Fig 1).There he had been treated with antibiotherapy and tube thoracostomy with a misdiagnosis of empyma. Chest radiograph after completion of treatment showed an air cyst together with a large mass in the left hemithorax (Fig 2), and he was referred to our department for further
Discussion
Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and occurs commonly in the head, neck, and urogenital organs. Primary pulmonary neoplasms are unusual in the pediatric age group, and RMS of the lung is one of the rarest. It accounts only 0.5% of childhood RMS2, and for 4.4% of childhood pulmonary neoplasms.1 Only 3 of 2,747 children included in the Intergroup Rhabdomyosarcoma Study had a primary pulmonary lesion.2, 3, 4
In review of the English-language literature, we found
References (27)
- et al.
Childhood primary pulmonary neoplasms
J Pediatr Surg
(1993) - et al.
Alveolar rhabdomyosarcoma of the lung in a child
J Pediatr Surg
(1995) - et al.
Primary pulmonary neoplasms of childhood: A review
Ann Thorac Surg
(1983) - et al.
Rhabdomyosarcoma arising within congenital pulmonary cysts: Report of three cases
J Pediatr Surg
(1992) - et al.
Primary pulmonary rhabdomyosarcoma of the bronchus
Ann Thorac Surg
(1971) - et al.
Embryonal rhabdomyosarcoma arising within a congenital broncogenic cyst in a child
J Pediatr Surg
(1981) - et al.
Combined therapy in childhood rhabdomyosarcoma: An analysis of 42 cases
J Pediatr Surg
(1969) - et al.
lobar emphysema, cystic adenomatoid malformation, pulmonary sequestration and broncogenic cyst in infancy and childhood: A clinical study group
J Pediatr Surg
(1974) - et al.
Primary pulmonary rhabdomyosarcoma: A case report and review of the literature
Hum Pathol
(1981) - et al.
Intrathoracic soft tissue sarcomas in children
Cancer
(1982)
Thoracic sarcomas in children
Ann Surg
The intergroup rhabdomyosarcoma study: A preliminary report
Cancer
Primary pulmonary rhabdomyosarcoma in a child, with a review of literature
J Surg Oncol
Cited by (128)
Thoracoscopic surgery for congenital lung malformations: Does previous infection really matter?
2021, Journal of Pediatric SurgeryCitation Excerpt :Theses reported tumors included PPB, adenocarcinoma, squamous cell carcinoma, rhabdomyosarcoma and mesenchymoma [28]. Another report of 33 cases of lung rhabdomyosarcoma found that 45% of them arose in preexisting CPAMs [29]. Duron et al. published a single-center study that included 63 interventions for CLMs.
Concurrent intrathoracic and extrathoracic congenital lung malformations
2021, Journal of Pediatric Surgery Case ReportsCitation Excerpt :The tumors developing within these lesions included pleuropulmonary blastoma, bronchoalveolar carcinoma, primary pulmonary rhabdomyosarcoma, squamous cell carcinoma, and mesenchymoma [19]. Another study reported 33 cases of primary pulmonary rhabdomyosarcoma, 15 of which occurred in the setting of a CLM [20]. Moreover, cases of fibrous mesothelioma and carcinoma have been reported in association with intralobar BPS [21].
MR Imaging of Lungs and Airways in Children:: Past and Present
2019, Magnetic Resonance Imaging Clinics of North AmericaAsymptomatic congenital lung malformations: Is nonoperative management a viable alternative?
2018, Journal of Pediatric SurgeryAssociation between congenital lung malformations and lung tumors in children and adults: A systematic review
2016, Journal of Thoracic Oncology
- *
Address reprint requests to Coşkun Özcan, Ege University, Faculty of Medicine, Department of Pediatric Surgery, 35100 Bornova-İzmir, Turkey.