Original ContributionsAcute thymic involution in fetuses and neonates with chorioamnionitis☆
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Cited by (125)
Small fetal thymus and adverse perinatal outcome in maternal vasculitis: A prospective case-control study
2023, Journal of Gynecology Obstetrics and Human ReproductionUltrasonographic evaluation of the fetal thymic-thoracic ratio and its association with conotruncal heart defects ✰
2022, Journal of Gynecology Obstetrics and Human ReproductionFirst trimester fetal thymus volume may predict preeclampsia
2021, Pregnancy HypertensionCitation Excerpt :According to the binary logistic regression analysis performed to predict preeclampsia, the low fetal thymus volume measured at 11–14 weeks suggests that it can be used as a predictive factor (P < .001). Smaller fetal thymus has been identified in many pregnancy-related diseases, including chorioamnionitis [9], malnutrition [10], and fetal inflammatory response syndrome [11]. Recently, there are studies showing smaller fetal thymus in diagnosed preeclampsia [12,13].
Assessment of the fetal thymus gland: Comparing MRI-acquired thymus volumes with 2D ultrasound measurements
2021, European Journal of Obstetrics and Gynecology and Reproductive BiologyThe fetal inflammatory response syndrome: the origins of a concept, pathophysiology, diagnosis, and obstetrical implications
2020, Seminars in Fetal and Neonatal MedicineCitation Excerpt :It is possible that the frequency of neutrophilia in human umbilical cord blood reflects at least, in part, the duration of exposure to an inflammatory stimulus. Thymic involution occurs after infection in the fetus and neonate [50–55]. Subclinical chorioamnionitis has been associated with a small thymus in very-low-birth-weight infants [50], possibly from acute fetal [51] and neonatal [51,52] involution.
Association between histological alterations in the thymus and sudden infant death syndrome
2018, Journal of Forensic and Legal Medicine
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Supported by a grant from the Italian Ministry of Education MURST (funding for research of National Interest) and from the University of Siena.