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Patent ductus arteriosus in the preterm infant: to treat or not to treat?

Journal of Perinatology volume 30, pages S31–S37 (2010)Cite this article

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Abstract

Pharmacological and/or surgical closure of a hemodynamically significant patent ductus arteriosus (PDA) in the very preterm infant has been the standard of care over the past few decades. However, the rationale for closure of PDA has recently been challenged. In this article, the factors that have fueled the controversy of the approach to the management of PDA and the gap in our knowledge are reviewed in detail. In addition, the pros and cons of the different treatment strategies applied in clinical care are evaluated with a focus on discussing the available evidence in the literature.

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Authors and Affiliations

  1. Department of Pediatrics, Neonatal-Perinatal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA

    S Noori

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Correspondence to S Noori.

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This paper resulted from the Evidence vs Experience in Neonatal Practices conference, 19 to 20 June 2009, sponsored by Dey, LP.

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Noori, S. Patent ductus arteriosus in the preterm infant: to treat or not to treat?. J Perinatol 30 (Suppl 1), S31–S37 (2010). https://doi.org/10.1038/jp.2010.97

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