Editorial
Timing of Caffeine Therapy in Very Low Birth Weight Infants

https://doi.org/10.1016/j.jpeds.2014.01.054Get rights and content

References (14)

There are more references available in the full text version of this article.

Cited by (22)

  • Weaning and extubation from mechanical ventilation

    2022, Goldsmith's Assisted Ventilation of the Neonate: An Evidence-Based Approach to Newborn Respiratory Care, Seventh Edition
  • National and international guidelines for neonatal caffeine use: Are they evidenced-based?

    2020, Seminars in Fetal and Neonatal Medicine
    Citation Excerpt :

    The observational studies suggest that caffeine initiated prior to three days of age in preterm infants, especially to those requiring positive airway pressure, is associated with greater benefit, but these data are confounded by indication. It remains unclear whether the safety and benefits of caffeine extend to extremely preterm infants who are fully dependent on mechanical ventilation in the first few days after birth, and who may have not met criteria for inclusion in the CAP trial [19]. Caffeine citrate as administered in the CAP trial was within the standard recommended dose (20 mg/kg loading, 5–10 mg/kg daily dose).

  • Drugs for the Prevention and Treatment of Bronchopulmonary Dysplasia

    2019, Clinics in Perinatology
    Citation Excerpt :

    Moreover, a nonsignificant trend toward higher mortality was observed in the early caffeine group, which led to early closure of the trial. At present, caffeine should be reserved for those neonates with apnea of prematurity or those who are ready for extubation or with significant lung disease.46 The currently available pharmacologic agents used to treat evolving or established BPD are summarized in Table 2.

  • Bronchopulmonary Dysplasia

    2018, Avery's Diseases of the Newborn: Tenth Edition
  • Bronchopulmonary Dysplasia

    2017, Avery's Diseases of the Newborn, Tenth Edition
View all citing articles on Scopus

The authors declare no conflicts of interest.

View full text