Original ArticleContinuous Glucose Monitoring in Newborn Babies at Risk of Hypoglycemia
Section snippets
Methods
We studied babies born at ≥32 weeks gestation who were at risk of hypoglycemia and admitted to the Waikato Hospital newborn intensive care unit. Babies remained in the study until they were no longer at risk of hypoglycemia or for 7 days, whichever came first. Babies were excluded from the study when there was a serious congenital abnormality or a skin condition that meant the continuous glucose monitor could not be attached. Whenever possible, consent was sought before birth from pregnant
Results
There were 102 babies enrolled in the study between December 2006 and February 2009 (Table I). One term baby had a seizure that was attributed to hypoglycemia before enrolling in the study. No other baby had any clinical signs that were attributed to neonatal hypoglycemia. Several babies were reported to be jittery, but none were hypoglycemic at these times.
The continuous glucose sensor was well tolerated for as long as 7 days. There were no infections, redness, or edema at the insertion sites.
Discussion
We determined the usefulness and reliability of continuous interstitial glucose monitoring in babies who were identified as being at risk of neonatal hypoglycemia and admitted to the newborn intensive care unit. Continuous glucose monitoring in this group of babies appears to be safe, well tolerated, and easy to use. There is good agreement between continuous interstitial and intermittent blood glucose measurements in 7 days of monitoring. Continuous glucose monitoring detects many more
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Supported by the Auckland Medical Research Foundation, the Waikato Medical Research Foundation, and the Rebecca Roberts Scholarship. The authors declare no conflicts of interest.