What is BPD in 2012 and what will BPD become?
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(1967) The New BPD: An arrest of lung development
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NICHD/NHLBI/ORD Workshop Summary – Bronchopulmonary dysplasia
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Patterns of respiratory disease during the first 2 postnatal weeks in extremely premature infants
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Cited by (70)
High-frequency ventilation
2022, Goldsmith's Assisted Ventilation of the Neonate: An Evidence-Based Approach to Newborn Respiratory Care, Seventh EditionIntraoperative management of the neonate
2022, Goldsmith's Assisted Ventilation of the Neonate: An Evidence-Based Approach to Newborn Respiratory Care, Seventh EditionManagement of the infant with bronchopulmonary dysplasia
2022, Goldsmith's Assisted Ventilation of the Neonate: An Evidence-Based Approach to Newborn Respiratory Care, Seventh EditionThe association between the microbes in the tracheobronchial aspirate fluid and bronchopulmonary dysplasia in preterm infants
2020, Pediatrics and NeonatologyCitation Excerpt :Bronchopulmonary dysplasia (BPD) is a chronic respiratory condition affecting >25% of infants with birth weights less than 1500 g,1,2 and is considered to be related to prematurity, inflammation, oxygen toxicity, infection and airway reactivity.3
Effects of hyperoxia exposure on the expression of Nrf2 and heme oxygenase-1 in lung tissues of premature rats
2020, Molecular and Cellular ProbesCitation Excerpt :On the 3rd of birth, the lung development of premature rats was similar to that of human gestational age at about 28 weeks. When exposed to high concentration of oxygen, the pulmonary morphology and clinical manifestations of newborn rats were very similar to BPD of premature infants [8,9]. In traditional BPD animal models, structural disorder, widening of alveolar space, reduction of alveolar number and simplification of alveoli could be observed with the prolongation of hyperoxia exposure time.
Recent advances in the pathogenesis of BPD
2018, Seminars in PerinatologyCitation Excerpt :Trends in the incidence of BPD are currently a matter of discussion, where improved survival of extremely preterm infants has been proposed to underlie increasing rates of BPD,3,4 whilst other studies report unchanged or reduced incidence of BPD.5–7 However, what is clear is that the spectrum of the affected population of infants has shifted, where the incidence of BPD is now lower in infants delivered at >28 weeks, whilst the incidence of BPD has increased in infants born at <28 weeks.8–11 This shift has also been accompanied by an evolving histopathological picture, where the key pathological hallmark of BPD today is an impairment in the development of the alveolar airspaces of the lung.8,9