Concepts, components & configurationsDeferred consent: Use in clinical resuscitation research
References (9)
- et al.
Lidoflazine administration to survivors of cardiac arrest
Ann Emerg Med
(1989) - Protection of Human Subjects, 45 CFR Pt 46, Subpt...
- et al.
Informed consent in resuscitation research
JAMA
(1981) - et al.
Deferred consent: A new approach for resusciation research
JAMA
(1986)
Cited by (48)
Long-term neurological outcomes in patients after out-of-hospital cardiac arrest
2016, ResuscitationCitation Excerpt :The date of patient's death was obtained from the National Health Insurance Service in South Korea. Neurologic status was classified according to the CPC,7,14,15 a scale that included five categories. CPC 1 was defined as conscious and alert with good cerebral performance; CPC 2 as conscious and alert with moderate cerebral performance; CPC 3 as conscious with severe cerebral disability; CPC 4 as comatose or in a persistent vegetative state; and CPC 5 as brain dead or dead by traditional criteria.
Ethical and regulatory considerations in the design of traumatic brain injury clinical studies
2015, Handbook of Clinical NeurologyCitation Excerpt :Even when family members are available, it is often difficult for them to make a thoughtful decision regarding research while also dealing with a sudden and unexpected traumatic event (Schats et al., 2003). To address this issue, the concept of deferred consent was used in the 1980s for resuscitation research (Brain Resuscitation Clinical Trial I Study Group, 1986; Abramson and Safar, 1990). Deferred consent made it possible to contact the family after the first dose of an experimental drug or placebo had been administered and later request consent to continue participation in the study (Abramson and Safar, 1990).
Ethical challenges and solutions regarding delirium studies in palliative care
2014, Journal of Pain and Symptom ManagementCitation Excerpt :Ultimately, the participant must make a decision, and the person obtaining consent, therefore, must have formulated an impression as to this individual's capacity, regardless of who else was additionally consulted. Deferred consent is used in emergency research and refers to the consent obtained after the treatment or intervention has commenced and when the patient has regained capacity or a proxy is engaged (deferred proxy).70,71 Delirium is clearly an acute condition that can be part of a terminal process, especially in PC settings, so this could be considered an appropriate solution.
Patients' perceptions of research in emergency settings: A study of survivors of sudden cardiac death
2009, Social Science and MedicineEthical considerations in neuroemergency clinical trials
2006, Handbook of Neuroemergency Clinical Trials
This study was supported by NIH Grant No. NS15295.
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19 hospital worldwide of the BRCT II Study Group. The BRCT II Study Group