The developmental outcome of children with antenatal mild isolated ventriculomegaly
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Cited by (109)
Mild ventriculomegaly from fetal consultation to neurodevelopmental assessment: A single center experience and review of the literature
2018, European Journal of Paediatric NeurologyEvaluation of choroid plexus with fetal magnetic resonance imaging: What happens in ventriculomegaly?
2018, Brain and DevelopmentCitation Excerpt :Ventricle diameter values within the 10–15 mm range are classified as mild VM, while values greater than 15 mm indicate severe VM [10–12]. Majority of neonates diagnosed with the isolated form of mild VM in the fetal period develop normally [13], but some may have transient or permanent cognitive, motor and psychosocial developmental delay [14–16]. Severe VM is generally accompanied by other CNS and non-CNS abnormalities and in such cases, poorer outcomes are to be expected [12].
Classification of Fetal Ventriculomegaly
2018, Volpe's Neurology of the NewbornCongenital Hydrocephalus
2018, Volpe's Neurology of the NewbornAltered white matter and cortical structure in neonates with antenatally diagnosed isolated ventriculomegaly
2016, NeuroImage: ClinicalCitation Excerpt :In the absence of other anomalies the term isolated VM is used but the aetiology of the dilation of these ventricles remains unknown (Kelly et al., 2001). However, there is evidence that long-term neurodevelopmental outcome is affected in cases of isolated VM (Melchiorre et al., 2009), with neurodevelopmental outcomes including difficulties in language (Falip et al., 2007; Sadan et al., 2007), cognitive (Bloom et al., 1997; Gomez-Arriaga et al., 2012; Leitner et al., 2009; Sadan et al., 2007), gross motor (Gomez-Arriaga et al., 2012; Leitner et al., 2009) and behavioural functions (Falip et al., 2007; Gomez-Arriaga et al., 2012; Leitner et al., 2009; Sadan et al., 2007). In adults, an association has been observed between mild enlargement of the ventricles and neuropsychiatric disorders such as autism (Palmen et al., 2005), attention deficit hyperactivity disorder (Lyoo et al., 1996) and schizophrenia (Wright et al., 2000); although it is uncertain whether the observed VM in these adults had its origins in foetal life.
Ultrasound for fetal ventriculomegaly
2013, Ultrasound ClinicsCitation Excerpt :The odds of normal long-term neurodevelopmental outcome have been reported to be between 81% and 100% when the atrial width is between 10 and 15 mm (pooled estimate 87%).22,44,46–51 Several series have reported an association between the severity of VM and neurologic outcome.41,47,48,52,53 For example, the neurologic outcome was normal in 93%, 75%, and 63% of surviving neonates with isolated mild (10–12 mm), moderate (12.1–14.9 mm), and severe (≥15 mm) VM present at birth.41