Female alloimmunization with antibodies known to cause hemolytic disease
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2021, Seminars in Vascular SurgeryCitation Excerpt :Like ABO types, Rh-type refers to proteins on surface of red blood cells [47]. Clinically, this system plays an important role in blood transfusion and erythroblastosis fetalis [47,48]. Recent studies also demonstrate a significant impact in COVID-19 infection and illness as well.
Alloimmunization in Pregnancy
2020, Immunologic Concepts in Transfusion MedicineRed Blood Cell Alloimmunization in the Pregnant Patient
2018, Transfusion Medicine ReviewsCitation Excerpt :Reported rates of alloimmunization in women of childbearing potential vary greatly depending upon the period and manner in which the data were collected. In the United States, a representative series of 22 102 blood samples from women of reproductive potential (age 15–44 years) identified RBC antibodies in 1.15%, of whom 18% had multiple antibodies [18]. Luckily, rates of clinically significant HDFN are much lower at 3/100000 to 80/100000 live births [19].
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