Fatty acid balance studies in premature infants fed human milk or formula: Effect of calcium supplementation*
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Cited by (97)
Effects of higher protein formula with improved fat blend on growth, feeding tolerance and nutritional biomarkers in preterm infants: A double-blind, randomized, controlled clinical trial
2022, Pediatrics and NeonatologyCitation Excerpt :Fats consisting of palmitic acid in the second position on the glycerol molecule (sn-2 palmitate) are resistant to digestion by pancreatic lipase and are therefore more easily absorbed in the intestinal tract. This can help promote feeding tolerance by preventing the formation of calcium soaps in stools and thereby improving calcium absorption.37,38 In this study, there was no apparent effect of the EF on stool consistency, except on FEF Day 21, when infants in the EF group had significantly softer stools compared to the CF group (P = 0.045, PP analysis set only but not ITT set).
Nutrition Assessment, Exposures, and Interventions for Very-Low-Birth-Weight Preterm Infants: An Evidence Analysis Center Scoping Review
2019, Journal of the Academy of Nutrition and DieteticsCitation Excerpt :Although the fat amount and type subtopic did have a large proportion of older articles, there has also been recent research, including nine articles in the last 10 years. Fifty-two observational articles73,88,92,107,108,111-157 examined outcomes associated with human milk vs formula intake in VLBW preterm infants in countries with developed economies (Figure 5). The literature on this topic was published consistently throughout this period.
ISSFAL Editorial (PLEFA)
2013, Prostaglandins Leukotrienes and Essential Fatty AcidsAccretion of Lipid in the Fetus and Newborn
2011, Fetal and Neonatal Physiology E-Book, Fourth EditionThe effects of enzymatic interesterification on the physical-chemical properties of blends of lard and soybean oil
2009, LWTCitation Excerpt :Due to the formation of such calcium soaps, stool hardness, constipation and, in some cases, bowel obstructions may occur. Thus, presence of palmitic acid acyl residues at the sn-2 position of HMF increases absorption of 16:0 in the infant and reduces calcium losses in the faeces (Chappel, Clandinin, Kearny-Volpe, Reichman, & Swyer, 1986). Therefore, such unique TAG molecules with palmitic acid esterified at the sn-2 position has a significant function in the development of infants.
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Supported by the Hospital for Sick Children Foundation, the Natural Sciences and Engineering Research Council of Canada, and the Annie L. Shields Fellowship program. Dr. Clandinin is a scholar of the Alberta Heritage Foundation for Medical Research.