Bacterial colonization of neonates admitted to an intensive care environment
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2019, American Journal of Infection ControlCitation Excerpt :Prematurity is a previously known risk factor that has been implicated in several outbreaks.14,18,22 This risk may be related to the incompletely established intestinal microbiota, making preterm infants more susceptible to colonization by microorganisms present in health care facilities.23 Preterm infants are also more susceptible to infection, owing to an immature immune system and less effective skin and mucosal barriers,5 which may be weakened as a consequence of invasive procedures that are performed more frequently in preterm infants admitted to NICUs.
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From the Department of Medicine, the Division of Infectious Diseases, and the Bacteriology Laboratory, Children's Hospital Medical Center; and the Department of Pediatrics, Harvard Medical School.