Elsevier

The Journal of Pediatrics

Volume 85, Issue 5, November 1974, Pages 684-685
The Journal of Pediatrics

Neonatal withdrawal symptoms associated with maternal use of propoxyphene hydrochloride (Darvon)

https://doi.org/10.1016/S0022-3476(74)80519-6Get rights and content

Withdrawal symptoms in a neonate whose mother had been a chronic user of propoxyphene hydrochloride have not, as far as we are aware, been reported. We observed withdrawal symptoms in a neonate at 20 hours of age; the mother had taken propoxyphene hydrochloride regularly for over 3 years prior to delivery. Since propoxyphene hydrochloride has well-described addicting potential and is closely related in structure to methadone, it is possible that the infant's symptoms were due to withdrawal from propoxyphene hydrochloride.

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