Newborn assessment and long-term adverse outcome: A systematic review☆,☆☆
Section snippets
Methods
We searched the medical literature from 1966 to September 1997 for studies examining the association between newborn assessment scores and long-term adverse outcome. DIMDI (Deutsches Institut für Medizinische Dokumentation und Information) was used as a host to search 20 common medical databases, including MEDLINE, on the association between Apgar score or cord blood pH and long-term adverse outcome. We searched for the following key words, alone or in combination: Apgar score, umbilical cord
Results
Our literature search resulted in 1312 abstracts. We read 281 articles, 213 derived from the search and 68 found among the references of these papers. Of these 281 studies, 81 provided sufficient numeric data to construct contingency tables. Thirty-nine of these 81 studies were subsequently excluded because they reported on patients already included in the meta-analysis, or because they used cutoff levels or outcome definitions that differed from those in most other studies. In the remaining 42
Comment
Although numerous studies address newborn assessment and serious adverse outcome, only a limited number provide sufficient data to construct contingency tables. Eight studies provided data on large cohorts of children4, 5, 6, 7, 8, 9, 10, 11; the others provided data on more restricted groups.2, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44 A reasonable criticism of studies such as ours is that data are pooled
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