Original articleA historical perspective of elevated systolic vs diastolic blood pressure from an epidemiological and clinical trial viewpoint☆
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Communicating efficacy information based on composite scores in direct-to-consumer prescription drug advertising
2016, Patient Education and CounselingCitation Excerpt :For drugs to be approved, pharmaceutical companies must objectively demonstrate to FDA “substantial evidence” for the efficacy of their drugs, typically through two well-controlled clinical trials [12,13]. In some cases, drug efficacy can be measured by a single endpoint, such as high blood pressure [14]. Often, however, efficacy is measured by multiple endpoints that are sometimes combined into an overall score called a composite score, or a composite endpoint [15,16].
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Supported in part by NIH Grant No. HL-07011.
Copyright © 1989 Published by Elsevier Inc.