The importance of volume of blood cultured in the detection of bacteremia and fungemia

https://doi.org/10.1016/0732-8893(83)90039-1Get rights and content

Abstract

An analysis was made on the basis of 5,389 isolates from 5,008 positive blood cultures of the relative yields from 10, 20, and 30 ml of blood. Average yields from cultures of 20 and 30 ml of blood were, respectively, 38 and 61% greater than that from 10 ml of blood.

References (6)

  • M.M. Hall et al.

    Comparison of three blood culture media with tryptic soy bruth

    J Clin Microbiol

    (1978)
  • M.M. Hall et al.

    Evaluation of a biphasic medium for blood cultures

    J Clin Microbiol

    (1979)
  • L.B. Reller et al.

    Cumitech 1A

There are more references available in the full text version of this article.

Cited by (100)

  • Development of new methods for detecting bloodstream pathogens

    2020, Clinical Microbiology and Infection
    Citation Excerpt :

    What is less well recognized is how defining these critical factors played a key role in the development of modern blood culture systems. The most important is the volume of blood cultured [10–22]. Contrary to widespread belief, the volume of blood cultured in infants and young children is an important variable, albeit one limited by the practical limitations in how much blood can be obtained from these patients [23–33].

  • Post-mortem detection of bacteremia using pairs of blood culture samples

    2017, Legal Medicine
    Citation Excerpt :

    We retrospectively investigated autopsy cases in which pairs of post-mortem blood culture samples were collected from two separate sites (both cardiac ventricles or the aorta and vena cava). The samples were collected from these locations because (i) these sites contain enough blood to allow the detection of microbiological organisms; (ii) this method allowed us to exclude skin-derived microorganisms; and (iii) when blood samples are collected from both cardiac ventricles, it is possible to take sufficient blood samples; i.e., 10–30 ml samples, which were recommended in previous articles [15–17]. Data regarding the patients’ characteristics, prior antibiotic therapy, survival time after illness onset, the interval from death to sample storage, the interval from death to the autopsy, and the blood culture results were collected.

  • Diagnosis of bacteraemia and growth times

    2015, International Journal of Infectious Diseases
View all citing articles on Scopus
View full text