Programmed cell death—II. Endocrine potentiation of the breakdown of the intersegmental muscles of silkmoths

doi:10.1016/0022-1910(64)90034-4

Journal of Insect Physiology

Volume 10, Issue 4, August 1964, Pages 643-649

https://doi.org/10.1016/0022-1910(64)90034-4 Get rights and content

Abstract

The abdominal intersegmental muscles of saturniid pupae are well preserved during the entire pupal period and throughout the three weeks required for the development of the adult moth. Then, within 48 hr after the emergence of the moth, the muscles break down and disappear. The breakdown is a result of developmental reactions within the muscles themselves; their dissolution, in this sense, is a carefully timed, final episode in their own metamorphosis. Thus, the endocrine conditions obtaining at the onset of adult development (the presence of ecdysone and the absence of juvenile hormone) dictate both the formation of all adult structures, including muscles, and the eventual death of the intersegmental muscles. If juvenile hormone is injected, the breakdown does not occur in the intersegmental muscles or in any of the other tissues which are normally destroyed during the pupal-adult transformation. The final signal for the initiation of breakdown does not appear to be endocrine in character. Thus, when pairs of pupae were joined in parabiosis so that they shared the same blood, the breakdown of muscle in one individual did not hasten or retard the breakdown in the other individual. This finding points to some further signalling system which triggers the initiation of cell death in the endocrinologically potentiated muscles.

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^☆: This investigation was supported, in part, by grants from the National Institutes of Health and the National Science Foundation.

^†: Present address: The Institute of Animal Genetics, Edinburgh, Scotland.

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Journal of Insect Physiology

Abstract

References (10)

A technique of transplantation for Drosophila

Amer. Nat.

Programed cell death in an insect. I. The histology and cytology of cell death

The physiology of insect diapause. II. The cytochrome oxidase system in relation to the diapause and development of the Cecropia silkworm

Biol. Bull., Woods Hole

The effects of temperature gradients on the pupal-adult transformation of silkworms

Biol. Bull., Woods Hole

Physiology of insect diapause: The role of the brain in the production and termination of pupal dormancy in the giant silkworm, Platysamia cecropia

Biol. Bull., Woods Hole

Cited by (275)

Unravelling joint cytotoxicity of ibuprofen and oxytetracycline on Chlamydomonas reinhardtii using a programmed cell death-related biomarkers panel

Surveying the landscape of emerging and understudied cell death mechanisms

Isolation, characterization of galactose-specific lectin from Odoiporus longicollis and its antibacterial and anticancer activities

Autoimmune diseases and apoptosis: Targets, challenges, and innovations

Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1

Cell Death in Cells Overlying Lateral Root Primordia Facilitates Organ Growth in Arabidopsis

Programmed cell death—II. Endocrine potentiation of the breakdown of the intersegmental muscles of silkmoths☆

Abstract

A technique of transplantation for Drosophila

Amer. Nat.

Programed cell death in an insect. I. The histology and cytology of cell death

The physiology of insect diapause. II. The cytochrome oxidase system in relation to the diapause and development of the Cecropia silkworm

Biol. Bull., Woods Hole

The effects of temperature gradients on the pupal-adult transformation of silkworms

Biol. Bull., Woods Hole

Physiology of insect diapause: The role of the brain in the production and termination of pupal dormancy in the giant silkworm, Platysamia cecropia

Biol. Bull., Woods Hole