Abstract
Objective
To determine whether pregnant women with amphetamine abuse developed more obstetric complications than non-drug abuser pregnant women.
Materials and methods
A retrospective case control study was undertaken. Pregnant women with amphetamine abuse who delivered between January 2002 and December 2003 were compared to control pregnant women.
Results
Pregnant women who abused amphetamine were more likely to develop anemia, preterm delivery, thick meconium stained amniotic fluid, and delivered small for gestational age neonates. However, cephalopelvic disproportion was less frequently found in the amphetamine abuse group.
Conclusion
Pregnant women who abuse amphetamine experience more obstetric complications than the non-drug abuser. This information may be useful to medical personnel who are caregivers of these pregnant women to provide adequate perinatal care.
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References
ACOG (2001) Intrauterine growth restriction. Clinical management guidelines for obstetrician-gynecologists. American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet 72:85–96
ACOG (2002) ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002. American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet 77:67–75
Beyrer C, Razak MH, Jittiwutikarn J, Suriyanon V, Vongchak T, Srirak N, Kawichai S, Tovanabutra S, Rungruengthanakit K, Sawanpanyalert P, Sripaipan T, Celentano DD (2004) Methamphetamine users in northern Thailand: changing demographics and risks for HIV and STD among treatment-seeking substance abusers. Int J STD AIDS 15:697–704
Billing L, Eriksson M, Jonsson B, Steneroth G, Zetterstrom R (1994) The influence of environmental factors on behavioural problems in 8-year-old children exposed to amphetamine during fetal life. Child Abuse Negl 18:3–9
Briggs GG, Freeman RK, Yaffe SJ (2005) Drugs in pregnancy and lactation, 7th edn. Lippincott Williams and Wilkins, Philadelphia
Cernerud L, Eriksson M, Jonsson B, Steneroth G, Zetterstrom R (1996) Amphetamine addiction during pregnancy: 14-year follow-up of growth and school performance. Acta Paediatr 85:204–208
Chomchai C, Na Manorom N, Watanarungsan P, Yossuck P, Chomchai S (2004) Methamphetamine abuse during pregnancy and its health impact on neonates born at Siriraj Hospital, Bangkok, Thailand. Southeast Asian J Trop Med Public Health 35:228–231
Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Gilstrap LCI, Wenstrom KD (2004) Williams Obstetrics, 7th edn. McGraw-Hill, New York
Furara SA, Carrick P, Armstrong D, Pairaudeau P, Pullan AM, Lindow SW (1999) The outcome of pregnancy associated with amphetamine use. J Obstet Gynaecol 19:377–380
Gillogley KM, Evans AT, Hansen RL, Samuels SJ, Batra KK (1990) The perinatal impact of cocaine, amphetamine, and opiate use detected by universal intrapartum screening. Am J Obstet Gynecol 163:1535–1542
Hawthorne JL, Maier RC (1993) Drug abuse in an obstetric population of a midsized city. South Med J 86:1334–1338
Kulsudjarit K (2004) Drug problem in southeast and southwest Asia. Ann N Y Acad Sci 1025:446–457
Ludlow JP, Evans SF, Hulse G (2004) Obstetric and perinatal outcomes in pregnancies associated with illicit substance abuse. Aust N Z J Obstet Gynaecol 44:302–306
McFarlane J, Parker B, Soeken K (1996) Physical abuse, smoking, and substance use during pregnancy: prevalence, interrelationships, and effects on birth weight. J Obstet Gynecol Neonatal Nurs 25:313–320
Nutt DJ (1996) Addiction: brain mechanisms and their treatment implications. Lancet 347:31–36
Ramamoorthy JD, Ramamoorthy S, Leibach FH, Ganapathy V (1995) Human placental monoamine transporters as targets for amphetamines. Am J Obstet Gynecol 173:1782–1787
Sattah MV, Supawitkul S, Dondero TJ, Kilmarx PH, Young NL, Mastro TD, Chaikummao S, Manopaiboon C, Griensven F (2002) Prevalence of and risk factors for methamphetamine use in northern Thai youth: results of an audio-computer-assisted self-interviewing survey with urine testing. Addiction 97:801–808
Thaithumyanon P, Limpongsanurak S, Praisuwanna P, Punnahitanon S (2005) Perinatal effects of amphetamine and heroin use during pregnancy on the mother and infant. J Med Assoc Thai 88:1506–1513
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Phupong, V., Darojn, D. Amphetamine abuse in pregnancy: the impact on obstetric outcome. Arch Gynecol Obstet 276, 167–170 (2007). https://doi.org/10.1007/s00404-007-0320-x
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DOI: https://doi.org/10.1007/s00404-007-0320-x