Skip to main content

Advertisement

Log in

Amphetamine abuse in pregnancy: the impact on obstetric outcome

  • Original Article
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Objective

To determine whether pregnant women with amphetamine abuse developed more obstetric complications than non-drug abuser pregnant women.

Materials and methods

A retrospective case control study was undertaken. Pregnant women with amphetamine abuse who delivered between January 2002 and December 2003 were compared to control pregnant women.

Results

Pregnant women who abused amphetamine were more likely to develop anemia, preterm delivery, thick meconium stained amniotic fluid, and delivered small for gestational age neonates. However, cephalopelvic disproportion was less frequently found in the amphetamine abuse group.

Conclusion

Pregnant women who abuse amphetamine experience more obstetric complications than the non-drug abuser. This information may be useful to medical personnel who are caregivers of these pregnant women to provide adequate perinatal care.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. ACOG (2001) Intrauterine growth restriction. Clinical management guidelines for obstetrician-gynecologists. American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet 72:85–96

    Google Scholar 

  2. ACOG (2002) ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002. American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet 77:67–75

    Article  Google Scholar 

  3. Beyrer C, Razak MH, Jittiwutikarn J, Suriyanon V, Vongchak T, Srirak N, Kawichai S, Tovanabutra S, Rungruengthanakit K, Sawanpanyalert P, Sripaipan T, Celentano DD (2004) Methamphetamine users in northern Thailand: changing demographics and risks for HIV and STD among treatment-seeking substance abusers. Int J STD AIDS 15:697–704

    Article  PubMed  CAS  Google Scholar 

  4. Billing L, Eriksson M, Jonsson B, Steneroth G, Zetterstrom R (1994) The influence of environmental factors on behavioural problems in 8-year-old children exposed to amphetamine during fetal life. Child Abuse Negl 18:3–9

    Article  PubMed  CAS  Google Scholar 

  5. Briggs GG, Freeman RK, Yaffe SJ (2005) Drugs in pregnancy and lactation, 7th edn. Lippincott Williams and Wilkins, Philadelphia

    Google Scholar 

  6. Cernerud L, Eriksson M, Jonsson B, Steneroth G, Zetterstrom R (1996) Amphetamine addiction during pregnancy: 14-year follow-up of growth and school performance. Acta Paediatr 85:204–208

    PubMed  CAS  Google Scholar 

  7. Chomchai C, Na Manorom N, Watanarungsan P, Yossuck P, Chomchai S (2004) Methamphetamine abuse during pregnancy and its health impact on neonates born at Siriraj Hospital, Bangkok, Thailand. Southeast Asian J Trop Med Public Health 35:228–231

    PubMed  Google Scholar 

  8. Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Gilstrap LCI, Wenstrom KD (2004) Williams Obstetrics, 7th edn. McGraw-Hill, New York

    Google Scholar 

  9. Furara SA, Carrick P, Armstrong D, Pairaudeau P, Pullan AM, Lindow SW (1999) The outcome of pregnancy associated with amphetamine use. J Obstet Gynaecol 19:377–380

    Article  PubMed  CAS  Google Scholar 

  10. Gillogley KM, Evans AT, Hansen RL, Samuels SJ, Batra KK (1990) The perinatal impact of cocaine, amphetamine, and opiate use detected by universal intrapartum screening. Am J Obstet Gynecol 163:1535–1542

    PubMed  CAS  Google Scholar 

  11. Hawthorne JL, Maier RC (1993) Drug abuse in an obstetric population of a midsized city. South Med J 86:1334–1338

    Article  PubMed  CAS  Google Scholar 

  12. Kulsudjarit K (2004) Drug problem in southeast and southwest Asia. Ann N Y Acad Sci 1025:446–457

    Article  PubMed  Google Scholar 

  13. Ludlow JP, Evans SF, Hulse G (2004) Obstetric and perinatal outcomes in pregnancies associated with illicit substance abuse. Aust N Z J Obstet Gynaecol 44:302–306

    Article  PubMed  Google Scholar 

  14. McFarlane J, Parker B, Soeken K (1996) Physical abuse, smoking, and substance use during pregnancy: prevalence, interrelationships, and effects on birth weight. J Obstet Gynecol Neonatal Nurs 25:313–320

    Article  PubMed  CAS  Google Scholar 

  15. Nutt DJ (1996) Addiction: brain mechanisms and their treatment implications. Lancet 347:31–36

    Article  PubMed  CAS  Google Scholar 

  16. Ramamoorthy JD, Ramamoorthy S, Leibach FH, Ganapathy V (1995) Human placental monoamine transporters as targets for amphetamines. Am J Obstet Gynecol 173:1782–1787

    Article  PubMed  CAS  Google Scholar 

  17. Sattah MV, Supawitkul S, Dondero TJ, Kilmarx PH, Young NL, Mastro TD, Chaikummao S, Manopaiboon C, Griensven F (2002) Prevalence of and risk factors for methamphetamine use in northern Thai youth: results of an audio-computer-assisted self-interviewing survey with urine testing. Addiction 97:801–808

    Article  PubMed  Google Scholar 

  18. Thaithumyanon P, Limpongsanurak S, Praisuwanna P, Punnahitanon S (2005) Perinatal effects of amphetamine and heroin use during pregnancy on the mother and infant. J Med Assoc Thai 88:1506–1513

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vorapong Phupong.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Phupong, V., Darojn, D. Amphetamine abuse in pregnancy: the impact on obstetric outcome. Arch Gynecol Obstet 276, 167–170 (2007). https://doi.org/10.1007/s00404-007-0320-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-007-0320-x

Keywords

Navigation