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Bacterial-induced activation of erythrocyte T-antigen complicating necrotising enterocolitis: A case report

  • Infectious Diseases
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Abstract

Erythrocyte Thomsen-Friedenreich cryptantigen (T-antigen) activation is not an uncommon event in infants with severe necrotising enterocolitis (NEC). Transfusion of these infants with blood products containing plasma carries the risk of causing intravascular haemolysis. T-antigen activation is easily detected using a rapid simple lectin agglutination test. Early recognition of T-antigen activation ensures the correct choice of plasma free transfusion therapy. We describe an infant with severe NEC complicated by T-antigen activation and haemolysis.

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Abbreviations

NEC:

necrotising enterocolitis

T-antigen:

Thomsen-Friedenreich cryptantigen

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Authors and Affiliations

  1. Department of Paediatrics Division of Neonatal-Perinatal Medicine, University of Western Ontario, 268 Grosvenor Street, N6A 4V2, London, Ontairo, Canada

    R. H. Mupanemunda & C. F. Kenyon

  2. Department of Medicine Division of Neonatal-Perinatal Medicine, University of Western Ontario, 268 Grosvenor Street, London, Ontario, Canada

    M. J. Inwood

  3. Department of Blood Transfusion Service Division of Neonatal-Perinatal Medicine, University of Western Ontario, 268 Grosvenor Street, London, Ontario, Canada

    K. Leigh

Authors
  1. R. H. Mupanemunda
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  2. C. F. Kenyon
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  3. M. J. Inwood
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  4. K. Leigh
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Mupanemunda, R.H., Kenyon, C.F., Inwood, M.J. et al. Bacterial-induced activation of erythrocyte T-antigen complicating necrotising enterocolitis: A case report. Eur J Pediatr 152, 325–326 (1993). https://doi.org/10.1007/BF01956745

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  • DOI: https://doi.org/10.1007/BF01956745

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