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Types of methicillin-resistantStaphylococcus aureus associated with high mortality in patients with bacteremia

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Abstract

Forty-seven strains of methicillin-resistantStaphylococcus aureus (MRSA) isolated from 47 patients with bacteremia were analyzed by chromosomal DNA digestion pattern using pulsed-field gel electrophoresis and evaluated for serological coagulase type, enterotoxin type, and toxic shock syndrome toxin-1 production. The mortality rate was significantly higher in the older patients (≥51 years of age) than in the younger patients (≤50 years of age) (50% vs. 4%, p=0.0007). Methicillin-resistantStaphylococcus aureus strains of serological coagulase type II were more likely to be associated with mortality in older patients than were strains of the other types (p=0.037).

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Authors and Affiliations

  1. Department of Clinical Laboratory Medicine, Nagoya University Hospital, Japan

    T. Nada, S. Ichiyama & N. Nakashima

  2. First Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, 466, Nagoya, Japan

    S. Ichiyama, Y. Iinuma & K. Shimokata

  3. Department of Bacteriology, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, 466, Nagoya, Japan

    M. Ohta & N. Kato

  4. Department of Clinical Laboratory Medicine, Anjo Kosei Hospital, Aichi Prefecture, Japan

    K. Inuzuka

  5. Department of Urology, Anjo Kosei Hospital, Aichi Prefecture, Japan

    H. Washida

Authors
  1. T. Nada
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  2. S. Ichiyama
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  3. Y. Iinuma
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  4. K. Inuzuka
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  5. H. Washida
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  6. M. Ohta
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  7. K. Shimokata
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  8. N. Kato
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  9. N. Nakashima
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Nada, T., Ichiyama, S., Iinuma, Y. et al. Types of methicillin-resistantStaphylococcus aureus associated with high mortality in patients with bacteremia. Eur. J. Clin. Microbiol. Infect. Dis. 15, 340–343 (1996). https://doi.org/10.1007/BF01695669

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  • DOI: https://doi.org/10.1007/BF01695669

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